Cavender D - Search Results

1

Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.

Xia M, Hou C, Pollack S, Brackley J, DeMong D, Pan M, Singer M, Matheis M, Olini G, Cavender D, Wachter M. Xia M, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5964-8. doi: 10.1016/j.bmcl.2007.07.065. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17869105

2

Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

Lagu B, Gerchak C, Pan M, Hou C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Lagu B, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4382-6. doi: 10.1016/j.bmcl.2007.01.115. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17587570

3

Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

Xia M, Hou C, DeMong DE, Pollack SR, Pan M, Brackley JA, Jain N, Gerchak C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Xia M, et al. Among authors: cavender d. J Med Chem. 2007 Nov 15;50(23):5561-3. doi: 10.1021/jm070902b. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929797

4

Substituted dipiperidine alcohols as potent CCR2 antagonists.

Xia M, Hou C, Demong D, Pollack S, Pan M, Brackley J, Singer M, Matheis M, Cavender D, Wachter M. Xia M, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3562-4. doi: 10.1016/j.bmcl.2008.05.010. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18487045

5

Synthesis and structure-activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists.

Xia M, Hou C, DeMong D, Pollack S, Pan M, Singer M, Matheis M, Murray W, Cavender D, Wachter M. Xia M, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6468-70. doi: 10.1016/j.bmcl.2008.10.061. Epub 2008 Oct 17. Bioorg Med Chem Lett. 2008. PMID: 18990568

6

Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45.

Beers SA, Malloy EA, Wu W, Wachter MP, Gunnia U, Cavender D, Harris C, Davis J, Brosius R, Pellegrino-Gensey JL, Siekierka J. Beers SA, et al. Among authors: cavender d. Bioorg Med Chem. 1997 Dec;5(12):2203-11. doi: 10.1016/s0968-0896(97)00174-0. Bioorg Med Chem. 1997. PMID: 9459018

7

In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions.

Hou C, Kirchner T, Singer M, Matheis M, Argentieri D, Cavender D. Hou C, et al. Among authors: cavender d. J Pharmacol Exp Ther. 2004 May;309(2):697-704. doi: 10.1124/jpet.103.060574. Epub 2004 Jan 16. J Pharmacol Exp Ther. 2004. PMID: 14730005

8

Simplified staurosporine analogs as potent JAK3 inhibitors.

Yang SM, Malaviya R, Wilson LJ, Argentieri R, Chen X, Yang C, Wang B, Cavender D, Murray WV. Yang SM, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2007 Jan 15;17(2):326-31. doi: 10.1016/j.bmcl.2006.10.062. Epub 2006 Oct 26. Bioorg Med Chem Lett. 2007. PMID: 17088059

9

6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor.

Henry JR, Rupert KC, Dodd JH, Turchi IJ, Wadsworth SA, Cavender DE, Fahmy B, Olini GC, Davis JE, Pellegrino-Gensey JL, Schafer PH, Siekierka JJ. Henry JR, et al. Among authors: cavender de. J Med Chem. 1998 Oct 22;41(22):4196-8. doi: 10.1021/jm980497b. J Med Chem. 1998. PMID: 9784093 No abstract available.

10

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.

Wadsworth SA, Cavender DE, Beers SA, Lalan P, Schafer PH, Malloy EA, Wu W, Fahmy B, Olini GC, Davis JE, Pellegrino-Gensey JL, Wachter MP, Siekierka JJ. Wadsworth SA, et al. Among authors: cavender de. J Pharmacol Exp Ther. 1999 Nov;291(2):680-7. J Pharmacol Exp Ther. 1999. PMID: 10525088

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