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A monoclonal antibody to O-acetyl-GD2 ganglioside and not to GD2 shows potent anti-tumor activity without peripheral nervous system cross-reactivity.
Alvarez-Rueda N, Desselle A, Cochonneau D, Chaumette T, Clemenceau B, Leprieur S, Bougras G, Supiot S, Mussini JM, Barbet J, Saba J, Paris F, Aubry J, Birklé S. Alvarez-Rueda N, et al. Among authors: leprieur s. PLoS One. 2011;6(9):e25220. doi: 10.1371/journal.pone.0025220. Epub 2011 Sep 22. PLoS One. 2011. PMID: 21966461 Free PMC article.