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Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections.
Hawryluk N, Robinson D, Shen Y, Kyne G, Bedore M, Menon S, Canan S, von Geldern T, Townson S, Gokool S, Ehrens A, Koschel M, Lhermitte-Vallarino N, Martin C, Hoerauf A, Hernandez G, Dalvie D, Specht S, Hübner MP, Scandale I. Hawryluk N, et al. Among authors: shen y. J Med Chem. 2022 Aug 25;65(16):11388-11403. doi: 10.1021/acs.jmedchem.2c00960. Epub 2022 Aug 16. J Med Chem. 2022. PMID: 35972896 Free PMC article.
Evolutionary dynamics of SARS-CoV-2 variants under strict non-pharmaceutical interventions - a population-based study.
Huo X, Cui L, Zhu L, Zhang J, Fan H, Yi Y, Zhao J, Ge Y, Wang S, Han X, Gao X, Qi X, Fu J, Li Z, Fan H, Yu H, Deng F, Zhao K, Zhu X, Hu J, Li J, Ai J, Kang G, Shen Y, Jin G, Wang F, Zhang Z, He M, Ding S, Wang Y, Dong Y, Huang Y, Yi C, Wang L, Jiao Y, Wang J, Li J, Liu H, Li J, Bao C, Wu M, Zhu F. Huo X, et al. Among authors: shen y. J Infect Dev Ctries. 2024 Dec 31;18(12.1):S214-S226. doi: 10.3855/jidc.19409. J Infect Dev Ctries. 2024. PMID: 39863937
The α-globin super-enhancer acts in an orientation-dependent manner.
Kassouf MT, Francis HS, Gosden M, Suciu MC, Downes DJ, Harrold C, Larke M, Oudelaar M, Cornell L, Blayney J, Telenius J, Xella B, Shen Y, Sousos N, Sharpe JA, Sloane-Stanley J, Smith AJH, Babbs C, Hughes JR, Higgs DR. Kassouf MT, et al. Among authors: shen y. Nat Commun. 2025 Jan 25;16(1):1033. doi: 10.1038/s41467-025-56380-1. Nat Commun. 2025. PMID: 39863595 Free article.
The 40S ribosomal subunit recycling complex modulates mitochondrial dynamics and endoplasmic reticulum - mitochondria tethering at mitochondrial fission/fusion hotspots.
Tahmasebinia F, Tang Y, Tang R, Zhang Y, Bonderer W, de Oliveira M, Laboret B, Chen S, Jian R, Jiang L, Snyder M, Chen CH, Shen Y, Liu Q, Liu B, Wu Z. Tahmasebinia F, et al. Among authors: shen y. Nat Commun. 2025 Jan 25;16(1):1021. doi: 10.1038/s41467-025-56346-3. Nat Commun. 2025. PMID: 39863576 Free article.
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