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Page 1
The discovery of long acting beta2-adrenoreceptor agonists.
Brown AD, Bunnage ME, Glossop PA, James K, Jones R, Lane CA, Lewthwaite RA, Mantell S, Perros-Huguet C, Price DA, Trevethick M, Webster R. Brown AD, et al. Among authors: mantell s. Bioorg Med Chem Lett. 2007 Jul 15;17(14):4012-5. doi: 10.1016/j.bmcl.2007.04.081. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17498952
The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists.
Brown AD, Bunnage ME, Glossop PA, James K, Jones R, Lane CA, Lewthwaite RA, Mantell S, Perros-Huguet C, Price DA, Trevethick M, Webster R. Brown AD, et al. Among authors: mantell s. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1280-3. doi: 10.1016/j.bmcl.2008.01.034. Epub 2008 Jan 12. Bioorg Med Chem Lett. 2008. PMID: 18226900
Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease.
Mantell SJ, Stephenson PT, Monaghan SM, Maw GN, Trevethick MA, Yeadon M, Keir RF, Walker DK, Jones RM, Selby MD, Batchelor DV, Rozze S, Chavaroche H, Hobson TJ, Dodd PG, Lemaitre A, Wright KN, Stuart EF. Mantell SJ, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1284-7. doi: 10.1016/j.bmcl.2008.01.033. Epub 2008 Jan 12. Bioorg Med Chem Lett. 2008. PMID: 18243699
SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data.
Mantell SJ, Stephenson PT, Monaghan SM, Maw GN, Trevethick MA, Yeadon M, Walker DK, Selby MD, Batchelor DV, Rozze S, Chavaroche H, Lemaitre A, Wright KN, Whitlock L, Stuart EF, Wright PA, Macintyre F. Mantell SJ, et al. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4471-5. doi: 10.1016/j.bmcl.2009.05.027. Epub 2009 May 12. Bioorg Med Chem Lett. 2009. PMID: 19501510
In vitro and in vivo SAR of pyrido[3,4-d]pyramid-4-ylamine based mGluR1 antagonists.
Mantell SJ, Gibson KR, Osborne SA, Maw GN, Rees H, Dodd PG, Greener B, Harbottle GW, Million WA, Poinsard C, England S, Carnell P, Betts AM, Monhemius R, Prime RL. Mantell SJ, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2190-4. doi: 10.1016/j.bmcl.2009.02.106. Epub 2009 Mar 3. Bioorg Med Chem Lett. 2009. PMID: 19289283
Beyond despair: Leveraging ecosystem restoration for psychosocial resilience.
Smith CS, DeMattia EA, Albright E, Bromberger AF, Hayward OG, Mackinson IJ, Mantell SA, McAdoo BG, McAfee D, McCollum A, Paxton AB, Roderer A, Stevenson K, Vidra RL, Zhao Z. Smith CS, et al. Among authors: mantell sa. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2307082121. doi: 10.1073/pnas.2307082121. Epub 2025 Jan 2. Proc Natl Acad Sci U S A. 2025. PMID: 39746002
34 results