Haines DC - Search Results

1

Obligatory intermolecular electron-transfer from FAD to FMN in dimeric P450BM-3.

Kitazume T, Haines DC, Estabrook RW, Chen B, Peterson JA. Kitazume T, et al. Among authors: haines dc. Biochemistry. 2007 Oct 23;46(42):11892-901. doi: 10.1021/bi701031r. Epub 2007 Sep 29. Biochemistry. 2007. PMID: 17902705

2

Interactions of substrates at the surface of P450s can greatly enhance substrate potency.

Hegde A, Haines DC, Bondlela M, Chen B, Schaffer N, Tomchick DR, Machius M, Nguyen H, Chowdhary PK, Stewart L, Lopez C, Peterson JA. Hegde A, et al. Among authors: haines dc. Biochemistry. 2007 Dec 11;46(49):14010-7. doi: 10.1021/bi701667m. Epub 2007 Nov 16. Biochemistry. 2007. PMID: 18004886

3

Bacillus megaterium CYP102A1 oxidation of acyl homoserine lactones and acyl homoserines.

Chowdhary PK, Keshavan N, Nguyen HQ, Peterson JA, González JE, Haines DC. Chowdhary PK, et al. Among authors: haines dc. Biochemistry. 2007 Dec 18;46(50):14429-37. doi: 10.1021/bi701945j. Epub 2007 Nov 20. Biochemistry. 2007. PMID: 18020460

4

Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.

Haines DC, Chen B, Tomchick DR, Bondlela M, Hegde A, Machius M, Peterson JA. Haines DC, et al. Biochemistry. 2008 Mar 25;47(12):3662-70. doi: 10.1021/bi7023964. Epub 2008 Feb 26. Biochemistry. 2008. PMID: 18298086

5

A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation.

Haines DC, Hegde A, Chen B, Zhao W, Bondlela M, Humphreys JM, Mullin DA, Tomchick DR, Machius M, Peterson JA. Haines DC, et al. Biochemistry. 2011 Oct 4;50(39):8333-41. doi: 10.1021/bi201099j. Epub 2011 Sep 6. Biochemistry. 2011. PMID: 21875028 Free PMC article.

6

Aluminum-substituted heme domain of P450BM-3 (BMP): introducing a heme-derived fluorescent probe for studies of substrate binding and protein-protein interactions in cytochromes P450.

Davydov DR, Ponomarev GV, Bobrovnikova-Marjon E, Haines DC, Peterson JA. Davydov DR, et al. Among authors: haines dc. Biotechnol Appl Biochem. 2013 Jan-Feb;60(1):41-51. doi: 10.1002/bab.1085. Biotechnol Appl Biochem. 2013. PMID: 23586991

7

The FMN-binding domain of cytochrome P450BM-3: resolution, reconstitution, and flavin analogue substitution.

Haines DC, Sevrioukova IF, Peterson JA. Haines DC, et al. Biochemistry. 2000 Aug 8;39(31):9419-29. doi: 10.1021/bi000255p. Biochemistry. 2000. PMID: 10924137

8

Pivotal role of water in the mechanism of P450BM-3.

Haines DC, Tomchick DR, Machius M, Peterson JA. Haines DC, et al. Biochemistry. 2001 Nov 13;40(45):13456-65. doi: 10.1021/bi011197q. Biochemistry. 2001. PMID: 11695892

9

Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling.

De Matteis F, Ballou DP, Coon MJ, Estabrook RW, Haines DC. De Matteis F, et al. Among authors: haines dc. Biochem Pharmacol. 2012 Aug 1;84(3):374-82. doi: 10.1016/j.bcp.2012.04.016. Epub 2012 Apr 28. Biochem Pharmacol. 2012. PMID: 22564776

10

Cloning, expression and characterization of a fast self-sufficient P450: CYP102A5 from Bacillus cereus.

Chowdhary PK, Alemseghed M, Haines DC. Chowdhary PK, et al. Among authors: haines dc. Arch Biochem Biophys. 2007 Dec 1;468(1):32-43. doi: 10.1016/j.abb.2007.09.010. Epub 2007 Sep 19. Arch Biochem Biophys. 2007. PMID: 17945181

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