Petrounia IP - Search Results

1

Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents.

Patch RJ, Brandt BM, Asgari D, Baindur N, Chadha NK, Georgiadis T, Cheung WS, Petrounia IP, Donatelli RR, Chaikin MA, Player MR. Patch RJ, et al. Among authors: petrounia ip. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4. doi: 10.1016/j.bmcl.2007.09.057. Epub 2007 Sep 19. Bioorg Med Chem Lett. 2007. PMID: 17904845

2

Discovery of novel FMS kinase inhibitors as anti-inflammatory agents.

Illig CR, Chen J, Wall MJ, Wilson KJ, Ballentine SK, Rudolph MJ, DesJarlais RL, Chen Y, Schubert C, Petrounia I, Crysler CS, Molloy CJ, Chaikin MA, Manthey CL, Player MR, Tomczuk BE, Meegalla SK. Illig CR, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8. doi: 10.1016/j.bmcl.2008.01.059. Epub 2008 Jan 19. Bioorg Med Chem Lett. 2008. PMID: 18242992

3

Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors.

Wilson KJ, Illig CR, Chen J, Wall MJ, Ballentine SK, DesJarlais RL, Chen Y, Schubert C, Donatelli R, Petrounia I, Crysler CS, Molloy CJ, Chaikin MA, Manthey CL, Player MR, Tomczuk BE, Meegalla SK. Wilson KJ, et al. Bioorg Med Chem Lett. 2010 Jul 1;20(13):3925-9. doi: 10.1016/j.bmcl.2010.05.013. Epub 2010 May 12. Bioorg Med Chem Lett. 2010. PMID: 20570147

4

2-Hydroxy-4,6-diamino-[1,3,5]triazines: a novel class of VEGF-R2 (KDR) tyrosine kinase inhibitors.

Baindur N, Chadha N, Brandt BM, Asgari D, Patch RJ, Schalk-Hihi C, Carver TE, Petrounia IP, Baumann CA, Ott H, Manthey C, Springer BA, Player MR. Baindur N, et al. Among authors: petrounia ip. J Med Chem. 2005 Mar 24;48(6):1717-20. doi: 10.1021/jm049372z. J Med Chem. 2005. PMID: 15771417

5

Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors.

Schubert C, Schalk-Hihi C, Struble GT, Ma HC, Petrounia IP, Brandt B, Deckman IC, Patch RJ, Player MR, Spurlino JC, Springer BA. Schubert C, et al. Among authors: petrounia ip. J Biol Chem. 2007 Feb 9;282(6):4094-101. doi: 10.1074/jbc.M608183200. Epub 2006 Nov 28. J Biol Chem. 2007. PMID: 17132624 Free article.

6

Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors.

Wall MJ, Chen J, Meegalla S, Ballentine SK, Wilson KJ, DesJarlais RL, Schubert C, Chaikin MA, Crysler C, Petrounia IP, Donatelli RR, Yurkow EJ, Boczon L, Mazzulla M, Player MR, Patch RJ, Manthey CL, Molloy C, Tomczuk B, Illig CR. Wall MJ, et al. Among authors: petrounia ip. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2097-102. doi: 10.1016/j.bmcl.2008.01.088. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18289848

7

Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors.

Huang H, Hutta DA, Hu H, DesJarlais RL, Schubert C, Petrounia IP, Chaikin MA, Manthey CL, Player MR. Huang H, et al. Among authors: petrounia ip. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2355-61. doi: 10.1016/j.bmcl.2008.02.070. Epub 2008 Mar 4. Bioorg Med Chem Lett. 2008. PMID: 18342505

8

The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: a new class of Aurora-A kinase inhibitors.

Moriarty KJ, Koblish HK, Garrabrant T, Maisuria J, Khalil E, Ali F, Petrounia IP, Crysler CS, Maroney AC, Johnson DL, Galemmo RA Jr. Moriarty KJ, et al. Among authors: petrounia ip. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5778-83. doi: 10.1016/j.bmcl.2006.08.080. Epub 2006 Sep 1. Bioorg Med Chem Lett. 2006. PMID: 16949284

9

Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor.

Xu G, Gaul MD, Liu Z, DesJarlais RL, Qi J, Wang W, Krosky D, Petrounia I, Milligan CM, Hermans A, Lu HR, Huang DZ, Xu JZ, Spurlino JC. Xu G, et al. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127602. doi: 10.1016/j.bmcl.2020.127602. Epub 2020 Oct 7. Bioorg Med Chem Lett. 2020. PMID: 33038544

10

Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.

Maryanoff BE, O'Neill JC, McComsey DF, Yabut SC, Luci DK, Jordan AD Jr, Masucci JA, Jones WJ, Abad MC, Gibbs AC, Petrounia I. Maryanoff BE, et al. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43. doi: 10.1021/ml200070g. eCollection 2011 Jul 14. ACS Med Chem Lett. 2011. PMID: 24900346 Free PMC article.

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