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Page 1
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.
Altenbach RJ, Liu H, Banfor PN, Browman KE, Fox GB, Fryer RM, Komater VA, Krueger KM, Marsh K, Miller TR, Pan JB, Pan L, Sun M, Thiffault C, Wetter J, Zhao C, Zhou D, Esbenshade TA, Hancock AA, Cowart MD. Altenbach RJ, et al. Among authors: miller tr. J Med Chem. 2007 Nov 1;50(22):5439-48. doi: 10.1021/jm0705051. Epub 2007 Oct 6. J Med Chem. 2007. PMID: 17918921
Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1.
Faghih R, Dwight W, Gentles R, Phelan K, Esbenshade TA, Ireland L, Miller TR, Kang CH, Fox GB, Gopalakrishnan SM, Hancock AA, Bennani YL. Faghih R, et al. Among authors: miller tr. Bioorg Med Chem Lett. 2002 Aug 5;12(15):2031-4. doi: 10.1016/s0960-894x(02)00309-8. Bioorg Med Chem Lett. 2002. PMID: 12113835
Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenoceptor agonist.
Altenbach RJ, Khilevich A, Kolasa T, Rohde JJ, Bhatia PA, Patel MV, Searle XB, Yang F, Bunnelle WH, Tietje K, Bayburt EK, Carroll WA, Meyer MD, Henry R, Buckner SA, Kuk J, Daza AV, Milicic IV, Cain JC, Kang CH, Ireland LM, Carr TL, Miller TR, Hancock AA, Nakane M, Esbenshade TA, Brune ME, O'Neill AB, Gauvin DM, Katwala SP, Holladay MW, Brioni JD, Sullivan JP. Altenbach RJ, et al. Among authors: miller tr. J Med Chem. 2004 Jun 3;47(12):3220-35. doi: 10.1021/jm030551a. J Med Chem. 2004. PMID: 15163201
In vitro optimization of structure activity relationships of analogues of A-331440 combining radioligand receptor binding assays and micronucleus assays of potential antiobesity histamine H3 receptor antagonists.
Hancock AA, Diehl MS, Faghih R, Bush EN, Krueger KM, Krishna G, Miller TR, Wilcox DM, Nguyen P, Pratt JK, Cowart MD, Esbenshade TA, Jacobson PB. Hancock AA, et al. Among authors: miller tr. Basic Clin Pharmacol Toxicol. 2004 Sep;95(3):144-52. doi: 10.1111/j.1742-7843.2004.950307.x. Basic Clin Pharmacol Toxicol. 2004. PMID: 15447739 Free article.
Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties.
Esbenshade TA, Fox GB, Krueger KM, Miller TR, Kang CH, Denny LI, Witte DG, Yao BB, Pan L, Wetter J, Marsh K, Bennani YL, Cowart MD, Sullivan JP, Hancock AA. Esbenshade TA, et al. Among authors: miller tr. J Pharmacol Exp Ther. 2005 Apr;313(1):165-75. doi: 10.1124/jpet.104.078303. Epub 2004 Dec 17. J Pharmacol Exp Ther. 2005. PMID: 15608078
758 results