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Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity.
Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI. Choi CS, et al. Among authors: wakil sj. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16480-5. doi: 10.1073/pnas.0706794104. Epub 2007 Oct 8. Proc Natl Acad Sci U S A. 2007. PMID: 17923673 Free PMC article.
Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.
Abu-Elheiga L, Matzuk MM, Kordari P, Oh W, Shaikenov T, Gu Z, Wakil SJ. Abu-Elheiga L, et al. Among authors: wakil sj. Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12011-6. doi: 10.1073/pnas.0505714102. Epub 2005 Aug 15. Proc Natl Acad Sci U S A. 2005. PMID: 16103361 Free PMC article.
The subcellular localization of acetyl-CoA carboxylase 2.
Abu-Elheiga L, Brinkley WR, Zhong L, Chirala SS, Woldegiorgis G, Wakil SJ. Abu-Elheiga L, et al. Among authors: wakil sj. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1444-9. doi: 10.1073/pnas.97.4.1444. Proc Natl Acad Sci U S A. 2000. PMID: 10677481 Free PMC article.
Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice.
Essop MF, Camp HS, Choi CS, Sharma S, Fryer RM, Reinhart GA, Guthrie PH, Bentebibel A, Gu Z, Shulman GI, Taegtmeyer H, Wakil SJ, Abu-Elheiga L. Essop MF, et al. Among authors: wakil sj. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H256-65. doi: 10.1152/ajpheart.91489.2007. Epub 2008 May 16. Am J Physiol Heart Circ Physiol. 2008. PMID: 18487439 Free PMC article.
Fatty acid metabolism: target for metabolic syndrome.
Wakil SJ, Abu-Elheiga LA. Wakil SJ, et al. J Lipid Res. 2009 Apr;50 Suppl(Suppl):S138-43. doi: 10.1194/jlr.R800079-JLR200. Epub 2008 Dec 1. J Lipid Res. 2009. PMID: 19047759 Free PMC article. Review.
166 results