O'Brien RM - Search Results

1

Long-range enhancers are required to maintain expression of the autoantigen islet-specific glucose-6-phosphatase catalytic subunit-related protein in adult mouse islets in vivo.

Wang Y, Flemming BP, Martin CC, Allen SR, Walters J, Oeser JK, Hutton JC, O'Brien RM. Wang Y, et al. Diabetes. 2008 Jan;57(1):133-41. doi: 10.2337/db07-0092. Epub 2007 Oct 17. Diabetes. 2008. PMID: 17942825

2

Molecular physiology and genetics of NIDDM. Importance of metabolic staging.

Granner DK, O'Brien RM. Granner DK, et al. Diabetes Care. 1992 Mar;15(3):369-95. doi: 10.2337/diacare.15.3.369. Diabetes Care. 1992. PMID: 1559407 Review.

3

PEPCK gene as model of inhibitory effects of insulin on gene transcription.

O'Brien RM, Granner DK. O'Brien RM, et al. Diabetes Care. 1990 Mar;13(3):327-39. doi: 10.2337/diacare.13.3.327. Diabetes Care. 1990. PMID: 2407480 Review.

4

A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin.

Streeper RS, Svitek CA, Chapman S, Greenbaum LE, Taub R, O'Brien RM. Streeper RS, et al. J Biol Chem. 1997 May 2;272(18):11698-701. doi: 10.1074/jbc.272.18.11698. J Biol Chem. 1997. PMID: 9115220 Free article.

5

Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription.

Streeper RS, Eaton EM, Ebert DH, Chapman SC, Svitek CA, O'Brien RM. Streeper RS, et al. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9208-13. doi: 10.1073/pnas.95.16.9208. Proc Natl Acad Sci U S A. 1998. PMID: 9689059 Free PMC article.

6

Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein.

Arden SD, Zahn T, Steegers S, Webb S, Bergman B, O'Brien RM, Hutton JC. Arden SD, et al. Diabetes. 1999 Mar;48(3):531-42. doi: 10.2337/diabetes.48.3.531. Diabetes. 1999. PMID: 10078553

7

Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.

Ebert DH, Bischof LJ, Streeper RS, Chapman SC, Svitek CA, Goldman JK, Mathews CE, Leiter EH, Hutton JC, O'Brien RM. Ebert DH, et al. Diabetes. 1999 Mar;48(3):543-51. doi: 10.2337/diabetes.48.3.543. Diabetes. 1999. PMID: 10078554

8

Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence.

Ayala JE, Streeper RS, Desgrosellier JS, Durham SK, Suwanichkul A, Svitek CA, Goldman JK, Barr FG, Powell DR, O'Brien RM. Ayala JE, et al. Diabetes. 1999 Sep;48(9):1885-9. doi: 10.2337/diabetes.48.9.1885. Diabetes. 1999. PMID: 10480625

9

Differential role of hepatocyte nuclear factor-1 in the regulation of glucose-6-phosphatase catalytic subunit gene transcription by cAMP in liver- and kidney-derived cell lines.

Streeper RS, Svitek CA, Goldman JK, O'Brien RM. Streeper RS, et al. J Biol Chem. 2000 Apr 21;275(16):12108-18. doi: 10.1074/jbc.275.16.12108. J Biol Chem. 2000. PMID: 10766845 Free article.

10

Characterization of the mouse islet-specific glucose-6-phosphatase catalytic subunit-related protein gene promoter by in situ footprinting: correlation with fusion gene expression in the islet-derived betaTC-3 and hamster insulinoma tumor cell lines.

Bischof LJ, Martin CC, Svitek CA, Stadelmaier BT, Hornbuckle LA, Goldman JK, Oeser JK, Hutton JC, O'Brien RM. Bischof LJ, et al. Diabetes. 2001 Mar;50(3):502-14. doi: 10.2337/diabetes.50.3.502. Diabetes. 2001. PMID: 11246869

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