Kellam B - Search Results

1

Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells.

Cordeaux Y, Briddon SJ, Alexander SP, Kellam B, Hill SJ. Cordeaux Y, et al. Among authors: kellam b. FASEB J. 2008 Mar;22(3):850-60. doi: 10.1096/fj.07-8180com. Epub 2007 Oct 24. FASEB J. 2008. PMID: 17959910

2

Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections.

Soukarieh F, Mashabi A, Richardson W, Oton EV, Romero M, Dubern JF, Robertson SN, Lucanto S, Markham-Lee Z, Sou T, Kukavica-Ibrulj I, Levesque RC, Bergstrom CAS, Halliday N, Kellam B, Emsley J, Heeb S, Williams P, Stocks MJ, Cámara M. Soukarieh F, et al. Among authors: kellam b. J Med Chem. 2024 Jan 25;67(2):1008-1023. doi: 10.1021/acs.jmedchem.3c00973. Epub 2024 Jan 3. J Med Chem. 2024. PMID: 38170170 Free PMC article.

3

Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level.

Briddon SJ, Middleton RJ, Yates AS, George MW, Kellam B, Hill SJ. Briddon SJ, et al. Among authors: kellam b. Faraday Discuss. 2004;126:197-207; discussion 245-54. doi: 10.1039/b307407b. Faraday Discuss. 2004. PMID: 14992407

4

Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells.

Briddon SJ, Middleton RJ, Cordeaux Y, Flavin FM, Weinstein JA, George MW, Kellam B, Hill SJ. Briddon SJ, et al. Among authors: kellam b. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4673-8. doi: 10.1073/pnas.0400420101. Epub 2004 Mar 16. Proc Natl Acad Sci U S A. 2004. PMID: 15070776 Free PMC article.

5

New fluorescent adenosine A1-receptor agonists that allow quantification of ligand-receptor interactions in microdomains of single living cells.

Middleton RJ, Briddon SJ, Cordeaux Y, Yates AS, Dale CL, George MW, Baker JG, Hill SJ, Kellam B. Middleton RJ, et al. Among authors: kellam b. J Med Chem. 2007 Feb 22;50(4):782-93. doi: 10.1021/jm061279i. Epub 2007 Jan 24. J Med Chem. 2007. PMID: 17249651

6

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.

Baker JG, Middleton R, Adams L, May LT, Briddon SJ, Kellam B, Hill SJ. Baker JG, et al. Among authors: kellam b. Br J Pharmacol. 2010 Feb;159(4):772-86. doi: 10.1111/j.1476-5381.2009.00488.x. Epub 2010 Jan 26. Br J Pharmacol. 2010. PMID: 20105183 Free PMC article.

7

Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells.

Briddon SJ, Kellam B, Hill SJ. Briddon SJ, et al. Among authors: kellam b. Methods Mol Biol. 2011;746:211-36. doi: 10.1007/978-1-61779-126-0_11. Methods Mol Biol. 2011. PMID: 21607859

8

Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors.

Baker JG, Adams LA, Salchow K, Mistry SN, Middleton RJ, Hill SJ, Kellam B. Baker JG, et al. Among authors: kellam b. J Med Chem. 2011 Oct 13;54(19):6874-87. doi: 10.1021/jm2008562. Epub 2011 Sep 16. J Med Chem. 2011. PMID: 21870877 Free PMC article.

9

Highly potent and selective fluorescent antagonists of the human adenosine A₃ receptor based on the 1,2,4-triazolo[4,3-a]quinoxalin-1-one scaffold.

Vernall AJ, Stoddart LA, Briddon SJ, Hill SJ, Kellam B. Vernall AJ, et al. Among authors: kellam b. J Med Chem. 2012 Feb 23;55(4):1771-82. doi: 10.1021/jm201722y. Epub 2012 Feb 13. J Med Chem. 2012. PMID: 22277057

10

Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.

Stoddart LA, Vernall AJ, Denman JL, Briddon SJ, Kellam B, Hill SJ. Stoddart LA, et al. Among authors: kellam b. Chem Biol. 2012 Sep 21;19(9):1105-15. doi: 10.1016/j.chembiol.2012.07.014. Chem Biol. 2012. PMID: 22999879 Free PMC article.

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