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Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors.
Renaud S, Pugacheva EM, Delgado MD, Braunschweig R, Abdullaev Z, Loukinov D, Benhattar J, Lobanenkov V. Renaud S, et al. Among authors: lobanenkov v. Nucleic Acids Res. 2007;35(21):7372-88. doi: 10.1093/nar/gkm896. Epub 2007 Oct 25. Nucleic Acids Res. 2007. PMID: 17962299 Free PMC article.
Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF.
Klenova EM, Chernukhin IV, El-Kady A, Lee RE, Pugacheva EM, Loukinov DI, Goodwin GH, Delgado D, Filippova GN, León J, Morse HC 3rd, Neiman PE, Lobanenkov VV. Klenova EM, et al. Among authors: lobanenkov vv. Mol Cell Biol. 2001 Mar;21(6):2221-34. doi: 10.1128/MCB.21.6.2221-2234.2001. Mol Cell Biol. 2001. PMID: 11238955 Free PMC article.
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity.
Filippova GN, Qi CF, Ulmer JE, Moore JM, Ward MD, Hu YJ, Loukinov DI, Pugacheva EM, Klenova EM, Grundy PE, Feinberg AP, Cleton-Jansen AM, Moerland EW, Cornelisse CJ, Suzuki H, Komiya A, Lindblom A, Dorion-Bonnet F, Neiman PE, Morse HC 3rd, Collins SJ, Lobanenkov VV. Filippova GN, et al. Among authors: lobanenkov vv. Cancer Res. 2002 Jan 1;62(1):48-52. Cancer Res. 2002. PMID: 11782357
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.
Loukinov DI, Pugacheva E, Vatolin S, Pack SD, Moon H, Chernukhin I, Mannan P, Larsson E, Kanduri C, Vostrov AA, Cui H, Niemitz EL, Rasko JE, Docquier FM, Kistler M, Breen JJ, Zhuang Z, Quitschke WW, Renkawitz R, Klenova EM, Feinberg AP, Ohlsson R, Morse HC 3rd, Lobanenkov VV. Loukinov DI, et al. Among authors: lobanenkov vv. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6806-11. doi: 10.1073/pnas.092123699. Proc Natl Acad Sci U S A. 2002. PMID: 12011441 Free PMC article.
Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.
Pant V, Kurukuti S, Pugacheva E, Shamsuddin S, Mariano P, Renkawitz R, Klenova E, Lobanenkov V, Ohlsson R. Pant V, et al. Among authors: lobanenkov v. Mol Cell Biol. 2004 Apr;24(8):3497-504. doi: 10.1128/MCB.24.8.3497-3504.2004. Mol Cell Biol. 2004. PMID: 15060168 Free PMC article.
119 results