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Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.
Lang SA, Moser C, Gaumann A, Klein D, Glockzin G, Popp FC, Dahlke MH, Piso P, Schlitt HJ, Geissler EK, Stoeltzing O. Lang SA, et al. Among authors: glockzin g. Clin Cancer Res. 2007 Nov 1;13(21):6459-68. doi: 10.1158/1078-0432.CCR-07-1104. Clin Cancer Res. 2007. PMID: 17975158
45 results