Klein D - Search Results

1

Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.

Lang SA, Moser C, Gaumann A, Klein D, Glockzin G, Popp FC, Dahlke MH, Piso P, Schlitt HJ, Geissler EK, Stoeltzing O. Lang SA, et al. Among authors: klein d. Clin Cancer Res. 2007 Nov 1;13(21):6459-68. doi: 10.1158/1078-0432.CCR-07-1104. Clin Cancer Res. 2007. PMID: 17975158

2

Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.

Lang SA, Gaumann A, Koehl GE, Seidel U, Bataille F, Klein D, Ellis LM, Bolder U, Hofstaedter F, Schlitt HJ, Geissler EK, Stoeltzing O. Lang SA, et al. Among authors: klein d. Int J Cancer. 2007 Apr 15;120(8):1803-10. doi: 10.1002/ijc.22442. Int J Cancer. 2007. PMID: 17230506

3

Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.

Lang SA, Klein D, Moser C, Gaumann A, Glockzin G, Dahlke MH, Dietmaier W, Bolder U, Schlitt HJ, Geissler EK, Stoeltzing O. Lang SA, et al. Among authors: klein d. Mol Cancer Ther. 2007 Mar;6(3):1123-32. doi: 10.1158/1535-7163.MCT-06-0628. Mol Cancer Ther. 2007. PMID: 17363505

4

Differences in the hepatic signal transcription pathway and cytokine expression between thermal injury and sepsis.

Klein D, Einspanier R, Bolder U, Jeschke MG. Klein D, et al. Shock. 2003 Dec;20(6):536-43. doi: 10.1097/01.shk.0000093345.68755.98. Shock. 2003. PMID: 14625478

5

Insulin attenuates the systemic inflammatory response in endotoxemic rats.

Jeschke MG, Klein D, Bolder U, Einspanier R. Jeschke MG, et al. Among authors: klein d. Endocrinology. 2004 Sep;145(9):4084-93. doi: 10.1210/en.2004-0592. Epub 2004 Jun 10. Endocrinology. 2004. PMID: 15192048

6

Effect of oxidized regenerated cellulose/collagen matrix on dermal and epidermal healing and growth factors in an acute wound.

Jeschke MG, Sandmann G, Schubert T, Klein D. Jeschke MG, et al. Among authors: klein d. Wound Repair Regen. 2005 May-Jun;13(3):324-31. doi: 10.1111/j.1067-1927.2005.130316.x. Wound Repair Regen. 2005. PMID: 15953053

7

Insulin attenuates the systemic inflammatory response to thermal trauma.

Jeschke MG, Einspanier R, Klein D, Jauch KW. Jeschke MG, et al. Among authors: klein d. Mol Med. 2002 Aug;8(8):443-50. Mol Med. 2002. PMID: 12435855 Free PMC article.

8

Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma.

Klein D, Schubert T, Horch RE, Jauch KW, Jeschke MG. Klein D, et al. Ann Surg. 2004 Aug;240(2):340-9. doi: 10.1097/01.sla.0000133353.57674.cd. Ann Surg. 2004. PMID: 15273560 Free PMC article.

9

Insulin decreases inflammatory signal transcription factor expression in primary human liver cells after LPS challenge.

Jeschke MG, Klein D, Thasler WE, Bolder U, Schlitt HJ, Jauch KW, Weiss TS. Jeschke MG, et al. Among authors: klein d. Mol Med. 2008 Jan-Feb;14(1-2):11-9. doi: 10.2119/2007-00062.Jeschke. Mol Med. 2008. PMID: 18037968 Free PMC article.

10

Liposomal gene transfer of multiple genes is more effective than gene transfer of a single gene.

Jeschke MG, Klein D. Jeschke MG, et al. Among authors: klein d. Gene Ther. 2004 May;11(10):847-55. doi: 10.1038/sj.gt.3302229. Gene Ther. 2004. PMID: 14961069

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