Sasková K - Search Results

1

Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants.

Kozísek M, Bray J, Rezácová P, Sasková K, Brynda J, Pokorná J, Mammano F, Rulísek L, Konvalinka J. Kozísek M, et al. Among authors: saskova k. J Mol Biol. 2007 Dec 7;374(4):1005-16. doi: 10.1016/j.jmb.2007.09.083. Epub 2007 Oct 3. J Mol Biol. 2007. PMID: 17977555

2

Potent inhibition of drug-resistant HIV protease variants by monoclonal antibodies.

Bartonová V, Král V, Sieglová I, Brynda J, Fábry M, Horejsí M, Kozísek M, Sasková KG, Konvalinka J, Sedlácek J, Rezácová P. Bartonová V, et al. Among authors: saskova kg. Antiviral Res. 2008 Jun;78(3):275-7. doi: 10.1016/j.antiviral.2008.01.009. Epub 2008 Feb 20. Antiviral Res. 2008. PMID: 18329737

3

Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region.

Kozísek M, Sasková KG, Rezácová P, Brynda J, van Maarseveen NM, De Jong D, Boucher CA, Kagan RM, Nijhuis M, Konvalinka J. Kozísek M, et al. Among authors: saskova kg. J Virol. 2008 Jun;82(12):5869-78. doi: 10.1128/JVI.02325-07. Epub 2008 Apr 9. J Virol. 2008. PMID: 18400858 Free PMC article.

4

Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir.

Sasková KG, Kozísek M, Lepsík M, Brynda J, Rezácová P, Václavíková J, Kagan RM, Machala L, Konvalinka J. Sasková KG, et al. Protein Sci. 2008 Sep;17(9):1555-64. doi: 10.1110/ps.036079.108. Epub 2008 Jun 17. Protein Sci. 2008. PMID: 18560011 Free PMC article.

5

Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir.

Sasková KG, Kozísek M, Rezácová P, Brynda J, Yashina T, Kagan RM, Konvalinka J. Sasková KG, et al. J Virol. 2009 Sep;83(17):8810-8. doi: 10.1128/JVI.00451-09. Epub 2009 Jun 17. J Virol. 2009. PMID: 19535439 Free PMC article.

6

Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease.

Kozísek M, Henke S, Sasková KG, Jacobs GB, Schuch A, Buchholz B, Müller V, Kräusslich HG, Rezácová P, Konvalinka J, Bodem J. Kozísek M, et al. Among authors: saskova kg. Antimicrob Agents Chemother. 2012 Aug;56(8):4320-30. doi: 10.1128/AAC.00465-12. Epub 2012 May 29. Antimicrob Agents Chemother. 2012. PMID: 22644035 Free PMC article.

7

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.

Sivá M, Svoboda M, Veverka V, Trempe JF, Hofmann K, Kožíšek M, Hexnerová R, Sedlák F, Belza J, Brynda J, Šácha P, Hubálek M, Starková J, Flaisigová I, Konvalinka J, Šašková KG. Sivá M, et al. Among authors: saskova kg. Sci Rep. 2016 Jul 27;6:30443. doi: 10.1038/srep30443. Sci Rep. 2016. PMID: 27461074 Free PMC article.

8

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.

Trempe JF, Šašková KG, Sivá M, Ratcliffe CD, Veverka V, Hoegl A, Ménade M, Feng X, Shenker S, Svoboda M, Kožíšek M, Konvalinka J, Gehring K. Trempe JF, et al. Among authors: saskova kg. Sci Rep. 2016 Sep 20;6:33671. doi: 10.1038/srep33671. Sci Rep. 2016. PMID: 27646017 Free PMC article.

9

Backbone (1)H, (13)C, and (15)N NMR assignment for the inactive form of the retroviral protease of the murine intracisternal A-type particle, inMIA-14 PR.

Motácková V, Kubícková M, Kozísek M, Sasková KG, Svec M, Zídek L, Sklenár V. Motácková V, et al. Among authors: saskova kg. Biomol NMR Assign. 2009 Dec;3(2):261-4. doi: 10.1007/s12104-009-9189-x. Biomol NMR Assign. 2009. PMID: 19856131

10

Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.

Ramirez J, Lectez B, Osinalde N, Sivá M, Elu N, Aloria K, Procházková M, Perez C, Martínez-Hernández J, Barrio R, Šašková KG, Arizmendi JM, Mayor U. Ramirez J, et al. Among authors: saskova kg. Hum Mol Genet. 2018 Jun 1;27(11):1955-1971. doi: 10.1093/hmg/ddy103. Hum Mol Genet. 2018. PMID: 29788202

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