Cruz AC - Search Results

1

Cutting edge: Rac GTPases sensitize activated T cells to die via Fas.

Ramaswamy M, Dumont C, Cruz AC, Muppidi JR, Gomez TS, Billadeau DD, Tybulewicz VL, Siegel RM. Ramaswamy M, et al. Among authors: cruz ac. J Immunol. 2007 Nov 15;179(10):6384-8. doi: 10.4049/jimmunol.179.10.6384. J Immunol. 2007. PMID: 17982024

2

Specific elimination of effector memory CD4+ T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains.

Ramaswamy M, Cruz AC, Cleland SY, Deng M, Price S, Rao VK, Siegel RM. Ramaswamy M, et al. Among authors: cruz ac. Cell Death Differ. 2011 Apr;18(4):712-20. doi: 10.1038/cdd.2010.155. Epub 2010 Dec 17. Cell Death Differ. 2011. PMID: 21164519 Free PMC article.

3

Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses.

Ramaswamy M, Cleland SY, Cruz AC, Siegel RM. Ramaswamy M, et al. Among authors: cruz ac. Results Probl Cell Differ. 2009;49:17-47. doi: 10.1007/400_2008_24. Results Probl Cell Differ. 2009. PMID: 19132321 Free PMC article. Review.

4

The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.

Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, O'Shea JJ, Al-Shamkhani A, Kaplan MH, Gery I, Siegel RM, Meylan F. Richard AC, et al. Among authors: cruz ac. J Immunol. 2015 Apr 15;194(8):3567-82. doi: 10.4049/jimmunol.1401220. Epub 2015 Mar 18. J Immunol. 2015. PMID: 25786692 Free PMC article.

5

Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction.

Cruz AC, Ramaswamy M, Ouyang C, Klebanoff CA, Sengupta P, Yamamoto TN, Meylan F, Thomas SK, Richoz N, Eil R, Price S, Casellas R, Rao VK, Lippincott-Schwartz J, Restifo NP, Siegel RM. Cruz AC, et al. Nat Commun. 2016 Dec 23;7:13895. doi: 10.1038/ncomms13895. Nat Commun. 2016. PMID: 28008916 Free PMC article.

6

Beyond Cell Death: New Functions for TNF Family Cytokines in Autoimmunity and Tumor Immunotherapy.

Yi F, Frazzette N, Cruz AC, Klebanoff CA, Siegel RM. Yi F, et al. Among authors: cruz ac. Trends Mol Med. 2018 Jul;24(7):642-653. doi: 10.1016/j.molmed.2018.05.004. Epub 2018 Jun 4. Trends Mol Med. 2018. PMID: 29880309 Free PMC article. Review.

7

Super-Resolution Imaging of Fas/CD95 Reorganization Induced by Membrane-Bound Fas Ligand Reveals Nanoscale Clustering Upstream of FADD Recruitment.

Frazzette N, Cruz AC, Wu X, Hammer JA, Lippincott-Schwartz J, Siegel RM, Sengupta P. Frazzette N, et al. Among authors: cruz ac. Cells. 2022 Jun 12;11(12):1908. doi: 10.3390/cells11121908. Cells. 2022. PMID: 35741037 Free PMC article.

8

Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.

Fu Q, Fu TM, Cruz AC, Sengupta P, Thomas SK, Wang S, Siegel RM, Wu H, Chou JJ. Fu Q, et al. Among authors: cruz ac. Mol Cell. 2016 Feb 18;61(4):602-613. doi: 10.1016/j.molcel.2016.01.009. Epub 2016 Feb 4. Mol Cell. 2016. PMID: 26853147 Free PMC article.

9

T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.

Yamamoto TN, Lee PH, Vodnala SK, Gurusamy D, Kishton RJ, Yu Z, Eidizadeh A, Eil R, Fioravanti J, Gattinoni L, Kochenderfer JN, Fry TJ, Aksoy BA, Hammerbacher JE, Cruz AC, Siegel RM, Restifo NP, Klebanoff CA. Yamamoto TN, et al. Among authors: cruz ac. J Clin Invest. 2019 Feb 25;129(4):1551-1565. doi: 10.1172/JCI121491. eCollection 2019 Feb 25. J Clin Invest. 2019. PMID: 30694219 Free PMC article.

10

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.

Fu TM, Li Y, Lu A, Li Z, Vajjhala PR, Cruz AC, Srivastava DB, DiMaio F, Penczek PA, Siegel RM, Stacey KJ, Egelman EH, Wu H. Fu TM, et al. Among authors: cruz ac. Mol Cell. 2016 Oct 20;64(2):236-250. doi: 10.1016/j.molcel.2016.09.009. Epub 2016 Oct 13. Mol Cell. 2016. PMID: 27746017 Free PMC article.

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