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Page 1
Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the gamma-aminobutyric acid-A (GABAA) alpha2 benzodiazepine receptor.
Taliani S, Cosimelli B, Da Settimo F, Marini AM, La Motta C, Simorini F, Salerno S, Novellino E, Greco G, Cosconati S, Marinelli L, Salvetti F, L'Abbate G, Trasciatti S, Montali M, Costa B, Martini C. Taliani S, et al. Among authors: montali m. J Med Chem. 2009 Jun 25;52(12):3723-34. doi: 10.1021/jm9001154. J Med Chem. 2009. PMID: 19469479
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists.
Di Stefano A, Sozio P, Cacciatore I, Cocco A, Giorgioni G, Costa B, Montali M, Lucacchini A, Martini C, Spoto G, Di Pietrantonio F, Di Matteo E, Pinnen F. Di Stefano A, et al. Among authors: montali m. J Med Chem. 2005 Apr 7;48(7):2646-54. doi: 10.1021/jm040889k. J Med Chem. 2005. PMID: 15801855
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.
Primofiore G, Taliani S, Da Settimo F, Marini AM, La Motta C, Simorini F, Patrizi MP, Sergianni V, Novellino E, Greco G, Cosimelli B, Calderone V, Montali M, Besnard F, Martini C. Primofiore G, et al. Among authors: montali m. J Med Chem. 2007 Apr 5;50(7):1627-34. doi: 10.1021/jm0607707. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335185
Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies.
Guerrini G, Ciciani G, Cambi G, Bruni F, Selleri S, Melani F, Montali M, Martini C, Ghelardini C, Norcini M, Costanzo A. Guerrini G, et al. Among authors: montali m. Bioorg Med Chem. 2008 Apr 15;16(8):4471-89. doi: 10.1016/j.bmc.2008.02.058. Epub 2008 Mar 5. Bioorg Med Chem. 2008. PMID: 18325771
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism.
Guerrini G, Ciciani G, Cambi G, Bruni F, Selleri S, Guarino C, Melani F, Montali M, Martini C, Ghelardini C, Norcini M, Costanzo A. Guerrini G, et al. Among authors: montali m. J Med Chem. 2009 Aug 13;52(15):4668-82. doi: 10.1021/jm801599a. J Med Chem. 2009. PMID: 19591485
New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on γ-aminobutyrric acid type A (GABA(A)) receptor. Design, synthesis, biological, and molecular modeling investigation.
Guerrini G, Ciciani G, Bruni F, Selleri S, Guarino C, Melani F, Montali M, Daniele S, Martini C, Ghelardini C, Norcini M, Ciattini S, Costanzo A. Guerrini G, et al. Among authors: montali m. J Med Chem. 2010 Nov 11;53(21):7532-48. doi: 10.1021/jm1001887. J Med Chem. 2010. PMID: 20939501
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist useful tools for therapy of mnemonic damage.
Guerrini G, Ciciani G, Cambi G, Bruni F, Selleri S, Besnard F, Montali M, Martini C, Ghelardini C, Galeotti N, Costanzo A. Guerrini G, et al. Among authors: montali m. Bioorg Med Chem. 2007 Apr 1;15(7):2573-86. doi: 10.1016/j.bmc.2007.01.053. Epub 2007 Feb 2. Bioorg Med Chem. 2007. PMID: 17306981
56 results