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Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen.
Mol Cancer Ther. 2007 Nov;6(11):2817-27. doi: 10.1158/1535-7163.MCT-07-0312. Epub 2007 Nov 7.
Mol Cancer Ther. 2007.
PMID: 17989318
Emerging principles for the development of resistance to antihormonal therapy: implications for the clinical utility of fulvestrant.
Ariazi EA, Lewis-Wambi JS, Gill SD, Pyle JR, Ariazi JL, Kim HR, Sharma CG, Cordera F, Shupp HA, Li T, Jordan VC.
Ariazi EA, et al. Among authors: shupp ha.
J Steroid Biochem Mol Biol. 2006 Dec;102(1-5):128-38. doi: 10.1016/j.jsbmb.2006.09.003. Epub 2006 Nov 7.
J Steroid Biochem Mol Biol. 2006.
PMID: 17085047
Free PMC article.
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The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.
Ariazi EA, Brailoiu E, Yerrum S, Shupp HA, Slifker MJ, Cunliffe HE, Black MA, Donato AL, Arterburn JB, Oprea TI, Prossnitz ER, Dun NJ, Jordan VC.
Ariazi EA, et al. Among authors: shupp ha.
Cancer Res. 2010 Feb 1;70(3):1184-94. doi: 10.1158/0008-5472.CAN-09-3068. Epub 2010 Jan 19.
Cancer Res. 2010.
PMID: 20086172
Free PMC article.
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Exploiting the apoptotic actions of oestrogen to reverse antihormonal drug resistance in oestrogen receptor positive breast cancer patients.
Craig Jordan V, Lewis-Wambi J, Kim H, Cunliffe H, Ariazi E, Sharma CG, Shupp HA, Swaby R.
Craig Jordan V, et al. Among authors: shupp ha.
Breast. 2007 Dec;16 Suppl 2(Suppl 2):S105-13. doi: 10.1016/j.breast.2007.07.020. Epub 2007 Aug 24.
Breast. 2007.
PMID: 17719781
Free PMC article.
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