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PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.
Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG. Huang G, et al. Among authors: growney jd. Nat Genet. 2008 Jan;40(1):51-60. doi: 10.1038/ng.2007.7. Epub 2007 Nov 11. Nat Genet. 2008. PMID: 17994017
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.
Gotlib J, Berubé C, Growney JD, Chen CC, George TI, Williams C, Kajiguchi T, Ruan J, Lilleberg SL, Durocher JA, Lichy JH, Wang Y, Cohen PS, Arber DA, Heinrich MC, Neckers L, Galli SJ, Gilliland DG, Coutré SE. Gotlib J, et al. Among authors: growney jd. Blood. 2005 Oct 15;106(8):2865-70. doi: 10.1182/blood-2005-04-1568. Epub 2005 Jun 21. Blood. 2005. PMID: 15972446 Free PMC article.
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss.
Liu H, Golji J, Brodeur LK, Chung FS, Chen JT, deBeaumont RS, Bullock CP, Jones MD, Kerr G, Li L, Rakiec DP, Schlabach MR, Sovath S, Growney JD, Pagliarini RA, Ruddy DA, MacIsaac KD, Korn JM, McDonald ER 3rd. Liu H, et al. Among authors: growney jd. Nat Med. 2019 Jan;25(1):95-102. doi: 10.1038/s41591-018-0302-5. Epub 2018 Dec 17. Nat Med. 2019. PMID: 30559422
Genomic sequence analysis of the mouse Naip gene array.
Endrizzi MG, Hadinoto V, Growney JD, Miller W, Dietrich WF. Endrizzi MG, et al. Among authors: growney jd. Genome Res. 2000 Aug;10(8):1095-102. doi: 10.1101/gr.10.8.1095. Genome Res. 2000. PMID: 10958627 Free PMC article.
Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
Reddy A, Growney JD, Wilson NS, Emery CM, Johnson JA, Ward R, Monaco KA, Korn J, Monahan JE, Stump MD, Mapa FA, Wilson CJ, Steiger J, Ledell J, Rickles RJ, Myer VE, Ettenberg SA, Schlegel R, Sellers WR, Huet HA, Lehár J. Reddy A, et al. Among authors: growney jd. PLoS One. 2015 Sep 17;10(9):e0138486. doi: 10.1371/journal.pone.0138486. eCollection 2015. PLoS One. 2015. PMID: 26378449 Free PMC article.
IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism.
Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, Growney JD, Vander Heiden MG, Murphy AN, Pagliarini R, Metallo CM. Grassian AR, et al. Among authors: growney jd. Cancer Res. 2014 Jun 15;74(12):3317-31. doi: 10.1158/0008-5472.CAN-14-0772-T. Epub 2014 Apr 22. Cancer Res. 2014. PMID: 24755473 Free PMC article.
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1.
Levell JR, Caferro T, Chenail G, Dix I, Dooley J, Firestone B, Fortin PD, Giraldes J, Gould T, Growney JD, Jones MD, Kulathila R, Lin F, Liu G, Mueller A, van der Plas S, Slocum K, Smith T, Terranova R, Touré BB, Tyagi V, Wagner T, Xie X, Xu M, Yang FS, Zhou LX, Pagliarini R, Cho YS. Levell JR, et al. Among authors: growney jd. ACS Med Chem Lett. 2016 Dec 16;8(2):151-156. doi: 10.1021/acsmedchemlett.6b00334. eCollection 2017 Feb 9. ACS Med Chem Lett. 2016. PMID: 28197303 Free PMC article.
24 results