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Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo.
Reddy N, Hernandez-Ilizaliturri FJ, Deeb G, Roth M, Vaughn M, Knight J, Wallace P, Czuczman MS. Reddy N, et al. Among authors: czuczman ms. Br J Haematol. 2008 Jan;140(1):36-45. doi: 10.1111/j.1365-2141.2007.06841.x. Epub 2007 Nov 9. Br J Haematol. 2008. PMID: 17995965 Free article.
Concurrent administration of granulocyte colony-stimulating factor or granulocyte-monocyte colony-stimulating factor enhances the biological activity of rituximab in a severe combined immunodeficiency mouse lymphoma model.
Hernandez-Ilizaliturri FJ, Jupudy V, Reising S, Repasky EA, Czuczman MS. Hernandez-Ilizaliturri FJ, et al. Among authors: czuczman ms. Leuk Lymphoma. 2005 Dec;46(12):1775-84. doi: 10.1080/17402520500182329. Leuk Lymphoma. 2005. PMID: 16263581
CD52 over-expression affects rituximab-associated complement-mediated cytotoxicity but not antibody-dependent cellular cytotoxicity: preclinical evidence that targeting CD52 with alemtuzumab may reverse acquired resistance to rituximab in non-Hodgkin lymphoma.
Cruz RI, Hernandez-Ilizaliturri FJ, Olejniczak S, Deeb G, Knight J, Wallace P, Thurberg BL, Kennedy W, Czuczman MS. Cruz RI, et al. Among authors: czuczman ms. Leuk Lymphoma. 2007 Dec;48(12):2424-36. doi: 10.1080/10428190701647879. Leuk Lymphoma. 2007. PMID: 18067019
The use of galiximab in non-Hodgkin lymphoma.
Vinjamaram S, Czuczman MS, Hernandez-Ilizaliturri FJ. Vinjamaram S, et al. Among authors: czuczman ms. Clin Lymphoma Myeloma. 2008 Oct;8(5):277-82. doi: 10.3816/CLM.2008.n.038. Clin Lymphoma Myeloma. 2008. PMID: 18854281 Review.
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.
Brem EA, Thudium K, Khubchandani S, Tsai PC, Olejniczak SH, Bhat S, Riaz W, Gu J, Iqbal A, Campagna R, Knight J, Mavis C, Hoskin P, Deeb G, Gibbs JF, Fetterly G, Czuczman MS, Hernandez-Ilizaliturri FJ. Brem EA, et al. Among authors: czuczman ms. Br J Haematol. 2011 Jun;153(5):599-611. doi: 10.1111/j.1365-2141.2011.08669.x. Epub 2011 Apr 15. Br J Haematol. 2011. PMID: 21492126 Free PMC article.
Biological effects and clinical significance of lenalidomide-induced tumour flare reaction in patients with chronic lymphocytic leukaemia: in vivo evidence of immune activation and antitumour response.
Chanan-Khan AA, Chitta K, Ersing N, Paulus A, Masood A, Sher T, Swaika A, Wallace PK, Mashtare TL Jr, Wilding G, Lee K, Czuczman MS, Borrello I, Bangia N. Chanan-Khan AA, et al. Among authors: czuczman ms. Br J Haematol. 2011 Nov;155(4):457-67. doi: 10.1111/j.1365-2141.2011.08882.x. Epub 2011 Oct 20. Br J Haematol. 2011. PMID: 22010965 Free PMC article. Clinical Trial.
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