Morishima-Kawashima M - Search Results

1

Abeta46 is processed to Abeta40 and Abeta43, but not to Abeta42, in the low density membrane domains.

Yagishita S, Morishima-Kawashima M, Ishiura S, Ihara Y. Yagishita S, et al. J Biol Chem. 2008 Jan 11;283(2):733-8. doi: 10.1074/jbc.M707103200. Epub 2007 Nov 16. J Biol Chem. 2008. PMID: 18024430 Free article.

2

Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein.

Sato T, Dohmae N, Qi Y, Kakuda N, Misonou H, Mitsumori R, Maruyama H, Koo EH, Haass C, Takio K, Morishima-Kawashima M, Ishiura S, Ihara Y. Sato T, et al. J Biol Chem. 2003 Jul 4;278(27):24294-301. doi: 10.1074/jbc.M211161200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707272 Free article.

3

Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.

Funamoto S, Morishima-Kawashima M, Tanimura Y, Hirotani N, Saido TC, Ihara Y. Funamoto S, et al. Biochemistry. 2004 Oct 26;43(42):13532-40. doi: 10.1021/bi049399k. Biochemistry. 2004. PMID: 15491160

4

DAPT-induced intracellular accumulations of longer amyloid beta-proteins: further implications for the mechanism of intramembrane cleavage by gamma-secretase.

Yagishita S, Morishima-Kawashima M, Tanimura Y, Ishiura S, Ihara Y. Yagishita S, et al. Biochemistry. 2006 Mar 28;45(12):3952-60. doi: 10.1021/bi0521846. Biochemistry. 2006. PMID: 16548522

5

Effects of human apolipoprotein E isoforms on the amyloid beta-protein concentration and lipid composition in brain low-density membrane domains.

Morishima-Kawashima M, Han X, Tanimura Y, Hamanaka H, Kobayashi M, Sakurai T, Yokoyama M, Wada K, Nukina N, Fujita SC, Ihara Y. Morishima-Kawashima M, et al. J Neurochem. 2007 May;101(4):949-58. doi: 10.1111/j.1471-4159.2006.04400.x. J Neurochem. 2007. PMID: 17472586 Free PMC article.

6

Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3.

Kang MS, Baek SH, Chun YS, Moore AZ, Landman N, Berman D, Yang HO, Morishima-Kawashima M, Osawa S, Funamoto S, Ihara Y, Di Paolo G, Park JH, Chung S, Kim TW. Kang MS, et al. Among authors: morishima kawashima m. J Biol Chem. 2013 Jul 19;288(29):20868-20882. doi: 10.1074/jbc.M112.445734. Epub 2013 May 30. J Biol Chem. 2013. PMID: 23723072 Free PMC article.

7

γ-Secretase associated with lipid rafts: multiple interactive pathways in the stepwise processing of β-carboxyl-terminal fragment.

Matsumura N, Takami M, Okochi M, Wada-Kakuda S, Fujiwara H, Tagami S, Funamoto S, Ihara Y, Morishima-Kawashima M. Matsumura N, et al. Among authors: morishima kawashima m. J Biol Chem. 2014 Feb 21;289(8):5109-21. doi: 10.1074/jbc.M113.510131. Epub 2013 Dec 28. J Biol Chem. 2014. PMID: 24375443 Free PMC article.

8

Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin.

Sawamura N, Morishima-Kawashima M, Waki H, Kobayashi K, Kuramochi T, Frosch MP, Ding K, Ito M, Kim TW, Tanzi RE, Oyama F, Tabira T, Ando S, Ihara Y. Sawamura N, et al. J Biol Chem. 2000 Sep 8;275(36):27901-8. doi: 10.1074/jbc.M004308200. J Biol Chem. 2000. PMID: 10846187 Free article.

9

Alzheimer's disease: beta-Amyloid protein and tau.

Morishima-Kawashima M, Ihara Y. Morishima-Kawashima M, et al. J Neurosci Res. 2002 Nov 1;70(3):392-401. doi: 10.1002/jnr.10355. J Neurosci Res. 2002. PMID: 12391602 Review.

10

Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.

Qi Y, Morishima-Kawashima M, Sato T, Mitsumori R, Ihara Y. Qi Y, et al. Biochemistry. 2003 Feb 4;42(4):1042-52. doi: 10.1021/bi0267590. Biochemistry. 2003. PMID: 12549925

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