Zhu H - Search Results

1

MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison.

Xie CY, Zhu H, Lin LP, Miao ZH, Geng MY, Cai YJ, Chen Y, Zhao HJ, Luo HB, Zhang XW, Fan LM, Shen YM, Ding J. Xie CY, et al. Among authors: zhu h. Mol Cancer Ther. 2007 Nov;6(11):3059-70. doi: 10.1158/1535-7163.MCT-07-0014. Mol Cancer Ther. 2007. PMID: 18025289

2

DNA damage, c-myc suppression and apoptosis induced by the novel topoisomerase II inhibitor, salvicine, in human breast cancer MCF-7 cells.

Lu HR, Meng LH, Huang M, Zhu H, Miao ZH, Ding J. Lu HR, et al. Among authors: zhu h. Cancer Chemother Pharmacol. 2005 Mar;55(3):286-94. doi: 10.1007/s00280-004-0877-z. Epub 2004 Nov 16. Cancer Chemother Pharmacol. 2005. PMID: 15592835

3

Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase.

Lu HR, Zhu H, Huang M, Chen Y, Cai YJ, Miao ZH, Zhang JS, Ding J. Lu HR, et al. Among authors: zhu h. Mol Pharmacol. 2005 Oct;68(4):983-94. doi: 10.1124/mol.105.011544. Epub 2005 Jul 15. Mol Pharmacol. 2005. PMID: 16024664

4

SH-7, a new synthesized shikonin derivative, exerting its potent antitumor activities as a topoisomerase inhibitor.

Yang F, Chen Y, Duan W, Zhang C, Zhu H, Ding J. Yang F, et al. Among authors: zhu h. Int J Cancer. 2006 Sep 1;119(5):1184-93. doi: 10.1002/ijc.21943. Int J Cancer. 2006. PMID: 16570288

5

Medicinal chemistry of probimane and MST-16: comparison of anticancer effects between bisdioxopiperazines.

Lu DY, Huang M, Xu CH, Zhu H, Xu B, Ding J. Lu DY, et al. Among authors: zhu h. Med Chem. 2006 Jul;2(4):369-75. doi: 10.2174/157340606777724095. Med Chem. 2006. PMID: 16848748

6

Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo.

Huang M, Gao H, Chen Y, Zhu H, Cai Y, Zhang X, Miao Z, Jiang H, Zhang J, Shen H, Lin L, Lu W, Ding J. Huang M, et al. Among authors: zhu h. Clin Cancer Res. 2007 Feb 15;13(4):1298-307. doi: 10.1158/1078-0432.CCR-06-1277. Epub 2007 Feb 7. Clin Cancer Res. 2007. PMID: 17287296

7

R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.

Zhu H, Huang M, Yang F, Chen Y, Miao ZH, Qian XH, Xu YF, Qin YX, Luo HB, Shen X, Geng MY, Cai YJ, Ding J. Zhu H, et al. Mol Cancer Ther. 2007 Feb;6(2):484-95. doi: 10.1158/1535-7163.MCT-06-0584. Mol Cancer Ther. 2007. PMID: 17308047

8

Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins.

Huang M, Miao ZH, Zhu H, Cai YJ, Lu W, Ding J. Huang M, et al. Among authors: zhu h. Mol Cancer Ther. 2008 Jun;7(6):1440-9. doi: 10.1158/1535-7163.MCT-07-2116. Mol Cancer Ther. 2008. PMID: 18566216

9

Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition.

Cai YJ, Lu JJ, Zhu H, Xie H, Huang M, Lin LP, Zhang XW, Ding J. Cai YJ, et al. Among authors: zhu h. Free Radic Biol Med. 2008 Sep 1;45(5):627-35. doi: 10.1016/j.freeradbiomed.2008.05.017. Epub 2008 May 28. Free Radic Biol Med. 2008. PMID: 18582559

10

Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity.

Feng JM, Zhu H, Zhang XW, Ding J, Miao ZH. Feng JM, et al. Among authors: zhu h. Cancer Biol Ther. 2008 Nov;7(11):1726-31. doi: 10.4161/cbt.7.11.6728. Epub 2008 Nov 4. Cancer Biol Ther. 2008. PMID: 18787399 Free article.

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