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Page 1
Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F.
Shide K, Shimoda HK, Kumano T, Karube K, Kameda T, Takenaka K, Oku S, Abe H, Katayose KS, Kubuki Y, Kusumoto K, Hasuike S, Tahara Y, Nagata K, Matsuda T, Ohshima K, Harada M, Shimoda K. Shide K, et al. Among authors: shimoda hk, shimoda k. Leukemia. 2008 Jan;22(1):87-95. doi: 10.1038/sj.leu.2405043. Epub 2007 Nov 22. Leukemia. 2008. PMID: 18033315
Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function.
Shimoda K, Kato K, Aoki K, Matsuda T, Miyamoto A, Shibamori M, Yamashita M, Numata A, Takase K, Kobayashi S, Shibata S, Asano Y, Gondo H, Sekiguchi K, Nakayama K, Nakayama T, Okamura T, Okamura S, Niho Y, Nakayama K. Shimoda K, et al. Immunity. 2000 Oct;13(4):561-71. doi: 10.1016/s1074-7613(00)00055-8. Immunity. 2000. PMID: 11070174 Free article.
Cutting edge: tyk2 is required for the induction and nuclear translocation of Daxx which regulates IFN-alpha-induced suppression of B lymphocyte formation.
Shimoda K, Kamesaki K, Numata A, Aoki K, Matsuda T, Oritani K, Tamiya S, Kato K, Takase K, Imamura R, Yamamoto T, Miyamoto T, Nagafuji K, Gondo H, Nagafuchi S, Nakayama K, Harada M. Shimoda K, et al. J Immunol. 2002 Nov 1;169(9):4707-11. doi: 10.4049/jimmunol.169.9.4707. J Immunol. 2002. PMID: 12391177
891 results