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Neurokinin-1 receptor antagonist (aprepitant) inhibits drug-resistant HIV-1 infection of macrophages in vitro.
Wang X, Douglas SD, Lai JP, Tuluc F, Tebas P, Ho WZ. Wang X, et al. Among authors: douglas sd. J Neuroimmune Pharmacol. 2007 Mar;2(1):42-8. doi: 10.1007/s11481-006-9059-6. Epub 2007 Jan 12. J Neuroimmune Pharmacol. 2007. PMID: 18040825
We have previously shown that CP-96,345, a neurokinin-1 receptor (NK-1R) antagonist, inhibits HIV-1 infection of macrophages in vitro by downregulating CCR5 expression (Lai JP, Ho WZ, Zhan GX, Yi Y, Collman RG, Douglas SD 2001). We have now investigated the effects …
We have previously shown that CP-96,345, a neurokinin-1 receptor (NK-1R) antagonist, inhibits HIV-1 infection of macrophages in vitro by dow …
Morphine enhances HIV infection of neonatal macrophages.
Li Y, Merrill JD, Mooney K, Song L, Wang X, Guo CJ, Savani RC, Metzger DS, Douglas SD, Ho WZ. Li Y, et al. Among authors: douglas sd. Pediatr Res. 2003 Aug;54(2):282-8. doi: 10.1203/01.PDR.0000074973.83826.4C. Epub 2003 May 7. Pediatr Res. 2003. PMID: 12736382 Free PMC article.
A randomized, placebo controlled, double masked phase IB study evaluating the safety and antiviral activity of aprepitant, a neurokinin-1 receptor antagonist in HIV-1 infected adults.
Tebas P, Tuluc F, Barrett JS, Wagner W, Kim D, Zhao H, Gonin R, Korelitz J, Douglas SD. Tebas P, et al. Among authors: douglas sd. PLoS One. 2011;6(9):e24180. doi: 10.1371/journal.pone.0024180. Epub 2011 Sep 8. PLoS One. 2011. PMID: 21931661 Free PMC article. Clinical Trial.
529 results