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145 results

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Page 1
Design and synthesis of a fluorescent muscarinic antagonist.
Jones LH, Randall A, Napier C, Trevethick M, Sreckovic S, Watson J. Jones LH, et al. Among authors: napier c. Bioorg Med Chem Lett. 2008 Jan 15;18(2):825-7. doi: 10.1016/j.bmcl.2007.11.022. Epub 2007 Nov 17. Bioorg Med Chem Lett. 2008. PMID: 18042383
Design and synthesis of long acting inhaled corticosteroids for the treatment of asthma.
Millan DS, Ballard SA, Chunn S, Dybowski JA, Fulton CK, Glossop PA, Guillabert E, Hewson CA, Jones RM, Lamb DJ, Napier CM, Payne-Cook TA, Renery ER, Selby MD, Tutt MF, Yeadon M. Millan DS, et al. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5826-30. doi: 10.1016/j.bmcl.2011.07.106. Epub 2011 Aug 11. Bioorg Med Chem Lett. 2011. PMID: 21880489
Overcoming HERG affinity in the discovery of the CCR5 antagonist maraviroc.
Price DA, Armour D, de Groot M, Leishman D, Napier C, Perros M, Stammen BL, Wood A. Price DA, et al. Among authors: napier c. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4633-7. doi: 10.1016/j.bmcl.2006.06.012. Epub 2006 Jun 16. Bioorg Med Chem Lett. 2006. PMID: 16782336
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity.
Dorr P, Westby M, Dobbs S, Griffin P, Irvine B, Macartney M, Mori J, Rickett G, Smith-Burchnell C, Napier C, Webster R, Armour D, Price D, Stammen B, Wood A, Perros M. Dorr P, et al. Among authors: napier c. Antimicrob Agents Chemother. 2005 Nov;49(11):4721-32. doi: 10.1128/AAC.49.11.4721-4732.2005. Antimicrob Agents Chemother. 2005. PMID: 16251317 Free PMC article.
CCR5 pharmacology methodologies and associated applications.
Mansfield R, Able S, Griffin P, Irvine B, James I, Macartney M, Miller K, Mills J, Napier C, Navratilova I, Perros M, Rickett G, Root H, van der Ryst E, Westby M, Dorr P. Mansfield R, et al. Among authors: napier c. Methods Enzymol. 2009;460:17-55. doi: 10.1016/S0076-6879(09)05202-1. Methods Enzymol. 2009. PMID: 19446719
The molecular cloning and functional expression of the dog CCR5.
Mosley M, Pullen S, Botham A, Gray A, Napier C, Mansfield R, Holbrook M. Mosley M, et al. Among authors: napier c. Vet Immunol Immunopathol. 2006 Oct 15;113(3-4):415-20. doi: 10.1016/j.vetimm.2006.05.009. Epub 2006 Jun 27. Vet Immunol Immunopathol. 2006. PMID: 16806494
145 results