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Phase I/II feasibility study evaluating the generation of leukemia-reactive cytotoxic T lymphocyte lines for treatment of patients with relapsed leukemia after allogeneic stem cell transplantation.
Marijt E, Wafelman A, van der Hoorn M, van Bergen C, Bongaerts R, van Luxemburg-Heijs S, van den Muijsenberg J, Wolbers JO, van der Werff N, Willemze R, Falkenburg F. Marijt E, et al. Among authors: willemze r. Haematologica. 2007 Jan;92(1):72-80. doi: 10.3324/haematol.10433. Haematologica. 2007. PMID: 17229638 Free article. Clinical Trial.
Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application.
Griffioen M, van Egmond HM, Barnby-Porritt H, van der Hoorn MA, Hagedoorn RS, Kester MG, Schwabe N, Willemze R, Falkenburg JH, Heemskerk MH. Griffioen M, et al. Among authors: willemze r. Haematologica. 2008 Oct;93(10):1535-43. doi: 10.3324/haematol.13067. Epub 2008 Sep 2. Haematologica. 2008. PMID: 18768532 Free article.
Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia.
Marijt WA, Heemskerk MH, Kloosterboer FM, Goulmy E, Kester MG, van der Hoorn MA, van Luxemburg-Heys SA, Hoogeboom M, Mutis T, Drijfhout JW, van Rood JJ, Willemze R, Falkenburg JH. Marijt WA, et al. Among authors: willemze r. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2742-7. doi: 10.1073/pnas.0530192100. Epub 2003 Feb 24. Proc Natl Acad Sci U S A. 2003. PMID: 12601144 Free PMC article.
804 results