Conolly R - Search Results

1

Computational toxicology--a state of the science mini review.

Kavlock RJ, Ankley G, Blancato J, Breen M, Conolly R, Dix D, Houck K, Hubal E, Judson R, Rabinowitz J, Richard A, Setzer RW, Shah I, Villeneuve D, Weber E. Kavlock RJ, et al. Among authors: conolly r. Toxicol Sci. 2008 May;103(1):14-27. doi: 10.1093/toxsci/kfm297. Epub 2007 Dec 7. Toxicol Sci. 2008. PMID: 18065772 Review.

2

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: II. Computational modeling.

Breen M, Villeneuve DL, Ankley GT, Bencic DC, Breen MS, Watanabe KH, Lloyd AL, Conolly RB. Breen M, et al. Toxicol Sci. 2013 Jun;133(2):234-47. doi: 10.1093/toxsci/kft067. Epub 2013 Mar 9. Toxicol Sci. 2013. PMID: 23475784

3

Editor's Highlight: Computational Modeling of Plasma Vitellogenin Alterations in Response to Aromatase Inhibition in Fathead Minnows.

Cheng WY, Zhang Q, Schroeder A, Villeneuve DL, Ankley GT, Conolly R. Cheng WY, et al. Among authors: conolly r. Toxicol Sci. 2016 Nov;154(1):78-89. doi: 10.1093/toxsci/kfw142. Epub 2016 Aug 7. Toxicol Sci. 2016. PMID: 27503384

4

Mechanistic computational model of steroidogenesis in H295R cells: role of oxysterols and cell proliferation to improve predictability of biochemical response to endocrine active chemical--metyrapone.

Breen M, Breen MS, Terasaki N, Yamazaki M, Lloyd AL, Conolly RB. Breen M, et al. Toxicol Sci. 2011 Sep;123(1):80-93. doi: 10.1093/toxsci/kfr167. Epub 2011 Jul 1. Toxicol Sci. 2011. PMID: 21725065

5

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: I. Data generation in a small fish model.

Villeneuve DL, Breen M, Bencic DC, Cavallin JE, Jensen KM, Makynen EA, Thomas LM, Wehmas LC, Conolly RB, Ankley GT. Villeneuve DL, et al. Toxicol Sci. 2013 Jun;133(2):225-33. doi: 10.1093/toxsci/kft068. Epub 2013 Mar 14. Toxicol Sci. 2013. PMID: 23492810

6

Computational model of the fathead minnow hypothalamic-pituitary-gonadal axis: Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals.

Breen M, Villeneuve DL, Ankley GT, Bencic D, Breen MS, Watanabe KH, Lloyd AL, Conolly RB. Breen M, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2016 May-Jun;183-184:36-45. doi: 10.1016/j.cbpc.2016.02.002. Epub 2016 Feb 12. Comp Biochem Physiol C Toxicol Pharmacol. 2016. PMID: 26875912

7

Mechanistic computational model of ovarian steroidogenesis to predict biochemical responses to endocrine active compounds.

Breen MS, Villeneuve DL, Breen M, Ankley GT, Conolly RB. Breen MS, et al. Ann Biomed Eng. 2007 Jun;35(6):970-81. doi: 10.1007/s10439-007-9309-7. Epub 2007 Apr 13. Ann Biomed Eng. 2007. PMID: 17436109

8

Physiologically based pharmacokinetic modeling of deltamethrin: development of a rat and human diffusion-limited model.

Godin SJ, DeVito MJ, Hughes MF, Ross DG, Scollon EJ, Starr JM, Setzer RW, Conolly RB, Tornero-Velez R. Godin SJ, et al. Among authors: conolly rb. Toxicol Sci. 2010 Jun;115(2):330-43. doi: 10.1093/toxsci/kfq051. Epub 2010 Mar 3. Toxicol Sci. 2010. PMID: 20200215

9

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology.

Conolly RB, Ankley GT, Cheng W, Mayo ML, Miller DH, Perkins EJ, Villeneuve DL, Watanabe KH. Conolly RB, et al. Environ Sci Technol. 2017 Apr 18;51(8):4661-4672. doi: 10.1021/acs.est.6b06230. Epub 2017 Apr 7. Environ Sci Technol. 2017. PMID: 28355063 Free PMC article.

10

Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action.

Ankley GT, Bencic DC, Breen MS, Collette TW, Conolly RB, Denslow ND, Edwards SW, Ekman DR, Garcia-Reyero N, Jensen KM, Lazorchak JM, Martinović D, Miller DH, Perkins EJ, Orlando EF, Villeneuve DL, Wang RL, Watanabe KH. Ankley GT, et al. Among authors: conolly rb. Aquat Toxicol. 2009 May 5;92(3):168-78. doi: 10.1016/j.aquatox.2009.01.013. Epub 2009 Feb 10. Aquat Toxicol. 2009. PMID: 19261338

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