Konrad M - Search Results

1

Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.

Segura-Peña D, Lichter J, Trani M, Konrad M, Lavie A, Lutz S. Segura-Peña D, et al. Among authors: konrad m. Structure. 2007 Dec;15(12):1555-66. doi: 10.1016/j.str.2007.09.025. Structure. 2007. PMID: 18073106 Free PMC article.

2

Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.

Gardberg A, Shuvalova L, Monnerjahn C, Konrad M, Lavie A. Gardberg A, et al. Among authors: konrad m. Structure. 2003 Oct;11(10):1265-77. doi: 10.1016/j.str.2003.09.003. Structure. 2003. PMID: 14527394 Free article.

3

Substrate-induced conformational changes in human UMP/CMP kinase.

Segura-Peña D, Sekulic N, Ort S, Konrad M, Lavie A. Segura-Peña D, et al. Among authors: konrad m. J Biol Chem. 2004 Aug 6;279(32):33882-9. doi: 10.1074/jbc.M401989200. Epub 2004 May 26. J Biol Chem. 2004. PMID: 15163660 Free article.

4

Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure.

Segura-Peña D, Lutz S, Monnerjahn C, Konrad M, Lavie A. Segura-Peña D, et al. Among authors: konrad m. J Mol Biol. 2007 May 25;369(1):129-41. doi: 10.1016/j.jmb.2007.02.104. Epub 2007 Mar 15. J Mol Biol. 2007. PMID: 17407781 Free PMC article.

5

Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains.

Li Y, Spangenberg O, Paarmann I, Konrad M, Lavie A. Li Y, et al. Among authors: konrad m. J Biol Chem. 2002 Feb 8;277(6):4159-65. doi: 10.1074/jbc.M110792200. Epub 2001 Nov 29. J Biol Chem. 2002. PMID: 11729206 Free article.

6

Structural characterization of the closed conformation of mouse guanylate kinase.

Sekulic N, Shuvalova L, Spangenberg O, Konrad M, Lavie A. Sekulic N, et al. Among authors: konrad m. J Biol Chem. 2002 Aug 16;277(33):30236-43. doi: 10.1074/jbc.M204668200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036965 Free article.

7

Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.

Ostermann N, Segura-Peña D, Meier C, Veit T, Monnerjahn C, Konrad M, Lavie A. Ostermann N, et al. Among authors: konrad m. Biochemistry. 2003 Mar 11;42(9):2568-77. doi: 10.1021/bi027302t. Biochemistry. 2003. PMID: 12614151

8

Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase.

Lavie A, Konrad M. Lavie A, et al. Among authors: konrad m. Mini Rev Med Chem. 2004 May;4(4):351-9. doi: 10.2174/1389557043403981. Mini Rev Med Chem. 2004. PMID: 15134538 Review.

9

Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization.

Godsey MH, Ort S, Sabini E, Konrad M, Lavie A. Godsey MH, et al. Among authors: konrad m. Biochemistry. 2006 Jan 17;45(2):452-61. doi: 10.1021/bi0518646. Biochemistry. 2006. PMID: 16401075

10

Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine.

Malito E, Sekulic N, Too WC, Konrad M, Lavie A. Malito E, et al. Among authors: konrad m. J Mol Biol. 2006 Nov 24;364(2):136-51. doi: 10.1016/j.jmb.2006.08.084. Epub 2006 Sep 3. J Mol Biol. 2006. PMID: 17007874 Free PMC article.

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