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Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors.
Bruckheimer EM, Fazenbaker CA, Gallagher S, Mulgrew K, Fuhrmann S, Coffman KT, Walsh W, Ready S, Cook K, Damschroder M, Kinch M, Kiener PA, Woods R, Gao C, Dall'Acqua W, Wu H, Coats S. Bruckheimer EM, et al. Neoplasia. 2009 Jun;11(6):509-17, 2 p following 517. doi: 10.1593/neo.81578. Neoplasia. 2009. PMID: 19484140 Free PMC article.
Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer.
Merritt WM, Kamat AA, Hwang JY, Bottsford-Miller J, Lu C, Lin YG, Coffey D, Spannuth WA, Nugent E, Han LY, Landen CN, Nick AM, Stone RL, Coffman K, Bruckheimer E, Broaddus RR, Gershenson DM, Coleman RL, Sood AK. Merritt WM, et al. Among authors: bruckheimer e. Cancer Biol Ther. 2010 Dec 15;10(12):1306-14. doi: 10.4161/cbt.10.12.13582. Epub 2010 Dec 15. Cancer Biol Ther. 2010. PMID: 20948320 Free PMC article.
Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer.
Landen CN Jr, Lu C, Han LY, Coffman KT, Bruckheimer E, Halder J, Mangala LS, Merritt WM, Lin YG, Gao C, Schmandt R, Kamat AA, Li Y, Thaker P, Gershenson DM, Parikh NU, Gallick GE, Kinch MS, Sood AK. Landen CN Jr, et al. Among authors: bruckheimer e. J Natl Cancer Inst. 2006 Nov 1;98(21):1558-70. doi: 10.1093/jnci/djj414. J Natl Cancer Inst. 2006. PMID: 17077358
A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice.
Boudreau MW, Duraki D, Wang L, Mao C, Kim JE, Henn MA, Tang B, Fanning SW, Kiefer J, Tarasow TM, Bruckheimer EM, Moreno R, Mousses S, Greene GL, Roy EJ, Park BH, Fan TM, Nelson ER, Hergenrother PJ, Shapiro DJ. Boudreau MW, et al. Sci Transl Med. 2021 Jul 21;13(603):eabf1383. doi: 10.1126/scitranslmed.abf1383. Sci Transl Med. 2021. PMID: 34290053 Free PMC article.
116 results