Wilson LJ - Search Results

1

beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents.

Yang SM, Scannevin RH, Wang B, Burke SL, Huang Z, Karnachi P, Wilson LJ, Rhodes KJ, Lagu B, Murray WV. Yang SM, et al. Among authors: wilson lj. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1140-5. doi: 10.1016/j.bmcl.2007.11.129. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18083558

2

Simplified staurosporine analogs as potent JAK3 inhibitors.

Yang SM, Malaviya R, Wilson LJ, Argentieri R, Chen X, Yang C, Wang B, Cavender D, Murray WV. Yang SM, et al. Among authors: wilson lj. Bioorg Med Chem Lett. 2007 Jan 15;17(2):326-31. doi: 10.1016/j.bmcl.2006.10.062. Epub 2006 Oct 26. Bioorg Med Chem Lett. 2007. PMID: 17088059

3

Mild and efficient Lewis acid-promoted detritylation in the synthesis of N-hydroxy amides: a concise synthesis of (-)-Cobactin T.

Yang SM, Lagu B, Wilson LJ. Yang SM, et al. Among authors: wilson lj. J Org Chem. 2007 Oct 12;72(21):8123-6. doi: 10.1021/jo701411d. Epub 2007 Sep 19. J Org Chem. 2007. PMID: 17880142

4

beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification.

Yang SM, Scannevin RH, Wang B, Burke SL, Wilson LJ, Karnachi P, Rhodes KJ, Lagu B, Murray WV. Yang SM, et al. Among authors: wilson lj. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1135-9. doi: 10.1016/j.bmcl.2007.11.119. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18086526

5

Synthetic staurosporines via a ring closing metathesis strategy as potent JAK3 inhibitors and modulators of allergic responses.

Wilson LJ, Malaviya R, Yang C, Argentieri R, Wang B, Chen X, Murray WV, Cavender D. Wilson LJ, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3333-8. doi: 10.1016/j.bmcl.2009.04.039. Epub 2009 Apr 18. Bioorg Med Chem Lett. 2009. PMID: 19427203

6

Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy.

Wilson LJ, Wang B, Yang SM, Scannevin RH, Burke SL, Karnachi P, Rhodes KJ, Murray WV. Wilson LJ, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6485-90. doi: 10.1016/j.bmcl.2011.08.068. Epub 2011 Aug 28. Bioorg Med Chem Lett. 2011. PMID: 21925881

7

Virtual screening to successfully identify novel janus kinase 3 inhibitors: a sequential focused screening approach.

Chen X, Wilson LJ, Malaviya R, Argentieri RL, Yang SM. Chen X, et al. Among authors: wilson lj. J Med Chem. 2008 Nov 13;51(21):7015-9. doi: 10.1021/jm800662z. Epub 2008 Oct 10. J Med Chem. 2008. PMID: 18844338

8

Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors.

Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Mosley CA, et al. Among authors: wilson lj. Bioorg Med Chem. 2009 Sep 1;17(17):6463-80. doi: 10.1016/j.bmc.2009.05.085. Epub 2009 Jul 5. Bioorg Med Chem. 2009. PMID: 19648014 Free PMC article.

9

Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties.

Nguyen HH, Kim MB, Wilson RJ, Butch CJ, Kuo KM, Miller EJ, Tahirovic YA, Jecs E, Truax VM, Wang T, Sum CS, Cvijic ME, Schroeder GM, Wilson LJ, Liotta DC. Nguyen HH, et al. Among authors: wilson rj, wilson lj. J Med Chem. 2018 Aug 23;61(16):7168-7188. doi: 10.1021/acs.jmedchem.8b00450. Epub 2018 Aug 15. J Med Chem. 2018. PMID: 30052039

10

Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling.

Ganesh T, Min J, Thepchatri P, Du Y, Li L, Lewis I, Wilson L, Fu H, Chiosis G, Dingledine R, Liotta D, Snyder JP, Sun A. Ganesh T, et al. Bioorg Med Chem. 2008 Jul 15;16(14):6903-10. doi: 10.1016/j.bmc.2008.05.047. Epub 2008 May 27. Bioorg Med Chem. 2008. PMID: 18571929 Free PMC article.

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