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Stereospecific synthesis and bio-activity of novel beta(3)-adrenoceptor agonists and inverse agonists.
Bioorg Med Chem. 2008 Mar 1;16(5):2473-88. doi: 10.1016/j.bmc.2007.11.060. Epub 2007 Nov 28.
Bioorg Med Chem. 2008.
PMID: 18083578
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists.
Perrone MG, Santandrea E, Giorgio E, Bleve L, Scilimati A, Tortorella P.
Perrone MG, et al. Among authors: bleve l.
Bioorg Med Chem. 2006 Feb 15;14(4):1207-14. doi: 10.1016/j.bmc.2005.09.046. Epub 2005 Oct 10.
Bioorg Med Chem. 2006.
PMID: 16216512
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The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists.
Perrone MG, Bleve L, Santandrea E, Vitale P, Niso M, Scilimati A.
Perrone MG, et al. Among authors: bleve l.
ChemMedChem. 2009 Dec;4(12):2080-97. doi: 10.1002/cmdc.200900292.
ChemMedChem. 2009.
PMID: 19882697
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Hyperinsulinemia and obese phenotype differently influence blood pressure in young normotensive patients with polycystic ovary syndrome.
Mioni R, Cà AD, Turra J, Azzolini S, Xamin N, Bleve L, Maffei P, Vettor R, Fallo F.
Mioni R, et al. Among authors: bleve l.
Endocrine. 2017 Feb;55(2):625-634. doi: 10.1007/s12020-016-0958-x. Epub 2016 May 3.
Endocrine. 2017.
PMID: 27142411
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