Yang SM - Search Results

1

beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification.

Yang SM, Scannevin RH, Wang B, Burke SL, Wilson LJ, Karnachi P, Rhodes KJ, Lagu B, Murray WV. Yang SM, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1135-9. doi: 10.1016/j.bmcl.2007.11.119. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18086526

2

Simplified staurosporine analogs as potent JAK3 inhibitors.

Yang SM, Malaviya R, Wilson LJ, Argentieri R, Chen X, Yang C, Wang B, Cavender D, Murray WV. Yang SM, et al. Among authors: yang c. Bioorg Med Chem Lett. 2007 Jan 15;17(2):326-31. doi: 10.1016/j.bmcl.2006.10.062. Epub 2006 Oct 26. Bioorg Med Chem Lett. 2007. PMID: 17088059

3

Mild and efficient Lewis acid-promoted detritylation in the synthesis of N-hydroxy amides: a concise synthesis of (-)-Cobactin T.

Yang SM, Lagu B, Wilson LJ. Yang SM, et al. J Org Chem. 2007 Oct 12;72(21):8123-6. doi: 10.1021/jo701411d. Epub 2007 Sep 19. J Org Chem. 2007. PMID: 17880142

4

Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs).

Zhang YM, Fan X, Yang SM, Scannevin RH, Burke SL, Rhodes KJ, Jackson PF. Zhang YM, et al. Among authors: yang sm. Bioorg Med Chem Lett. 2008 Jan 1;18(1):405-8. doi: 10.1016/j.bmcl.2007.10.049. Epub 2007 Oct 18. Bioorg Med Chem Lett. 2008. PMID: 17980583

5

beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents.

Yang SM, Scannevin RH, Wang B, Burke SL, Huang Z, Karnachi P, Wilson LJ, Rhodes KJ, Lagu B, Murray WV. Yang SM, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1140-5. doi: 10.1016/j.bmcl.2007.11.129. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18083558

6

Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy.

Wilson LJ, Wang B, Yang SM, Scannevin RH, Burke SL, Karnachi P, Rhodes KJ, Murray WV. Wilson LJ, et al. Among authors: yang sm. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6485-90. doi: 10.1016/j.bmcl.2011.08.068. Epub 2011 Aug 28. Bioorg Med Chem Lett. 2011. PMID: 21925881

7

Virtual screening to successfully identify novel janus kinase 3 inhibitors: a sequential focused screening approach.

Chen X, Wilson LJ, Malaviya R, Argentieri RL, Yang SM. Chen X, et al. Among authors: yang sm. J Med Chem. 2008 Nov 13;51(21):7015-9. doi: 10.1021/jm800662z. Epub 2008 Oct 10. J Med Chem. 2008. PMID: 18844338

8

4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.

Yang SM, Tang Y, Zhang R, Lu H, Kuo GH, Gaul MD, Li Y, Ho G, Conway JG, Liang Y, Lenhard JM, Demarest KT, Murray WV. Yang SM, et al. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6773-6. doi: 10.1016/j.bmcl.2013.09.096. Epub 2013 Oct 9. Bioorg Med Chem Lett. 2013. PMID: 24153205

9

4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: part 2. Pyridazine-based analogs.

Yang SM, Tang Y, Rano T, Lu H, Kuo GH, Gaul MD, Li Y, Ho G, Lang W, Conway JG, Liang Y, Lenhard JM, Demarest KT, Murray WV. Yang SM, et al. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1437-41. doi: 10.1016/j.bmcl.2013.12.075. Epub 2013 Dec 27. Bioorg Med Chem Lett. 2014. PMID: 24405703

10

Discovery and lead identification of quinazoline-based BRD4 inhibitors.

Yang SM, Urban DJ, Yoshioka M, Strovel JW, Fletcher S, Wang AQ, Xu X, Shah P, Hu X, Hall MD, Jadhav A, Maloney DJ. Yang SM, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3483-3488. doi: 10.1016/j.bmcl.2018.08.039. Epub 2018 Aug 31. Bioorg Med Chem Lett. 2018. PMID: 30268702 Free PMC article.

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