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Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses.
Bonta PI, van Tiel CM, Vos M, Pols TW, van Thienen JV, Ferreira V, Arkenbout EK, Seppen J, Spek CA, van der Poll T, Pannekoek H, de Vries CJ. Bonta PI, et al. Among authors: pols tw. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2288-94. doi: 10.1161/01.ATV.0000238346.84458.5d. Epub 2006 Jul 27. Arterioscler Thromb Vasc Biol. 2006. PMID: 16873729
Nuclear receptor Nurr1 is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation.
Bonta PI, Pols TW, van Tiel CM, Vos M, Arkenbout EK, Rohlena J, Koch KT, de Maat MP, Tanck MW, de Winter RJ, Pannekoek H, Biessen EA, Bot I, de Vries CJ. Bonta PI, et al. Among authors: pols tw. Circulation. 2010 May 11;121(18):2023-32. doi: 10.1161/CIRCULATIONAHA.109.885673. Epub 2010 Apr 26. Circulation. 2010. PMID: 20421523
6-mercaptopurine inhibits atherosclerosis in apolipoprotein e*3-leiden transgenic mice through atheroprotective actions on monocytes and macrophages.
Pols TW, Bonta PI, Pires NM, Otermin I, Vos M, de Vries MR, van Eijk M, Roelofsen J, Havekes LM, Quax PH, van Kuilenburg AB, de Waard V, Pannekoek H, de Vries CJ. Pols TW, et al. Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1591-7. doi: 10.1161/ATVBAHA.110.205674. Epub 2010 Apr 22. Arterioscler Thromb Vasc Biol. 2010. PMID: 20413732
20 results