Routhier EL - Search Results

1

Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin.

Hassan R, Ebel W, Routhier EL, Patel R, Kline JB, Zhang J, Chao Q, Jacob S, Turchin H, Gibbs L, Phillips MD, Mudali S, Iacobuzio-Donahue C, Jaffee EM, Moreno M, Pastan I, Sass PM, Nicolaides NC, Grasso L. Hassan R, et al. Among authors: routhier el. Cancer Immun. 2007 Dec 19;7:20. Cancer Immun. 2007. PMID: 18088084 Free PMC article.

2

Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha.

Ebel W, Routhier EL, Foley B, Jacob S, McDonough JM, Patel RK, Turchin HA, Chao Q, Kline JB, Old LJ, Phillips MD, Nicolaides NC, Sass PM, Grasso L. Ebel W, et al. Among authors: routhier el. Cancer Immun. 2007 Mar 9;7:6. Cancer Immun. 2007. PMID: 17346028 Free PMC article.

3

Morphogenics as a tool for target discovery and drug development.

Nicolaides NC, Ebel W, Kline B, Chao Q, Routhier E, Sass PM, Grasso L. Nicolaides NC, et al. Ann N Y Acad Sci. 2005 Nov;1059:86-96. doi: 10.1196/annals.1339.029. Ann N Y Acad Sci. 2005. PMID: 16382047 Review.

4

Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.

Li J, Sai T, Berger M, Chao Q, Davidson D, Deshmukh G, Drozdowski B, Ebel W, Harley S, Henry M, Jacob S, Kline B, Lazo E, Rotella F, Routhier E, Rudolph K, Sage J, Simon P, Yao J, Zhou Y, Kavuru M, Bonfield T, Thomassen MJ, Sass PM, Nicolaides NC, Grasso L. Li J, et al. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3557-62. doi: 10.1073/pnas.0511285103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505368 Free PMC article.

5

Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration.

Tomkowicz B, Rybinski K, Foley B, Ebel W, Kline B, Routhier E, Sass P, Nicolaides NC, Grasso L, Zhou Y. Tomkowicz B, et al. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):17965-70. doi: 10.1073/pnas.0705647104. Epub 2007 Nov 6. Proc Natl Acad Sci U S A. 2007. PMID: 17986615 Free PMC article.

6

Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B.

Drozdowski B, Zhou Y, Kline B, Spidel J, Chan YY, Albone E, Turchin H, Chao Q, Henry M, Balogach J, Routhier E, Bavari S, Nicolaides NC, Sass PM, Grasso L. Drozdowski B, et al. J Immune Based Ther Vaccines. 2010 Dec 21;8:9. doi: 10.1186/1476-8518-8-9. J Immune Based Ther Vaccines. 2010. PMID: 21176153 Free PMC article.

7

Developing novel biopharmaceutical products through morphogenics.

Nicolaides NC, Sass PM, Chao Q, Kline JB, Ebel W, Routhier E, Zhou Y, Grasso L. Nicolaides NC, et al. Expert Opin Drug Discov. 2007 Dec;2(12):1619-29. doi: 10.1517/17460441.2.12.1619. Expert Opin Drug Discov. 2007. PMID: 23488905

8

Use of a stable-isotope-labeled reporter peptide and antioxidants for reliable quantification of methionine oxidation in a monoclonal antibody by liquid chromatography/mass spectrometry.

Kang P, Mezhebovsky T, Chen W, McCardle JA, Zhang S, Sullivan EP, Sass PM, Routhier E. Kang P, et al. Rapid Commun Mass Spectrom. 2016 Jul 30;30(14):1734-1742. doi: 10.1002/rcm.7646. Rapid Commun Mass Spectrom. 2016. PMID: 28328036

9

An Intercompany Perspective on Biopharmaceutical Drug Product Robustness Studies.

Morar-Mitrica S, Adams ML, Crotts G, Wurth C, Ihnat PM, Tabish T, Antochshuk V, DiLuzio W, Dix DB, Fernandez JE, Gupta K, Fleming MS, He B, Kranz JK, Liu D, Narasimhan C, Routhier E, Taylor KD, Truong N, Stokes ESE. Morar-Mitrica S, et al. J Pharm Sci. 2018 Feb;107(2):529-542. doi: 10.1016/j.xphs.2017.10.017. Epub 2017 Oct 23. J Pharm Sci. 2018. PMID: 29074375

10

hob1+, the fission yeast homolog of Bin1, is dispensable for endocytosis or actin organization, but required for the response to starvation or genotoxic stress.

Routhier EL, Donover PS, Prendergast GC. Routhier EL, et al. Oncogene. 2003 Feb 6;22(5):637-48. doi: 10.1038/sj.onc.1206162. Oncogene. 2003. PMID: 12569356

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