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Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation.
Shiraishi Y, Asano K, Niimi K, Fukunaga K, Wakaki M, Kagyo J, Takihara T, Ueda S, Nakajima T, Oguma T, Suzuki Y, Shiomi T, Sayama K, Kagawa S, Ikeda E, Hirai H, Nagata K, Nakamura M, Miyasho T, Ishizaka A. Shiraishi Y, et al. Among authors: hirai h. J Immunol. 2008 Jan 1;180(1):541-9. doi: 10.4049/jimmunol.180.1.541. J Immunol. 2008. PMID: 18097056
Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor.
Shiraishi Y, Asano K, Nakajima T, Oguma T, Suzuki Y, Shiomi T, Sayama K, Niimi K, Wakaki M, Kagyo J, Ikeda E, Hirai H, Yamaguchi K, Ishizaka A. Shiraishi Y, et al. Among authors: hirai h. J Pharmacol Exp Ther. 2005 Mar;312(3):954-60. doi: 10.1124/jpet.104.078212. Epub 2004 Nov 4. J Pharmacol Exp Ther. 2005. PMID: 15528449
CRTH2 is a critical regulator of neutrophil migration and resistance to polymicrobial sepsis.
Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T. Ishii M, et al. Among authors: hirai h. J Immunol. 2012 Jun 1;188(11):5655-64. doi: 10.4049/jimmunol.1102330. Epub 2012 Apr 27. J Immunol. 2012. PMID: 22544936 Free PMC article.
1,862 results