Gaponenko V - Search Results

1

Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target.

Timofeeva OA, Gaponenko V, Lockett SJ, Tarasov SG, Jiang S, Michejda CJ, Perantoni AO, Tarasova NI. Timofeeva OA, et al. Among authors: gaponenko v. ACS Chem Biol. 2007 Dec 21;2(12):799-809. doi: 10.1021/cb700186x. ACS Chem Biol. 2007. PMID: 18154267

2

Peptide structure stabilization by membrane anchoring and its general applicability to the development of potent cell-permeable inhibitors.

Johannessen L, Remsberg J, Gaponenko V, Adams KM, Barchi JJ Jr, Tarasov SG, Jiang S, Tarasova NI. Johannessen L, et al. Among authors: gaponenko v. Chembiochem. 2011 Apr 11;12(6):914-21. doi: 10.1002/cbic.201000563. Epub 2011 Mar 1. Chembiochem. 2011. PMID: 21365731 Free PMC article.

3

Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles.

Tarasov SG, Gaponenko V, Howard OM, Chen Y, Oppenheim JJ, Dyba MA, Subramaniam S, Lee Y, Michejda C, Tarasova NI. Tarasov SG, et al. Among authors: gaponenko v. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9798-803. doi: 10.1073/pnas.1014598108. Epub 2011 May 31. Proc Natl Acad Sci U S A. 2011. PMID: 21628584 Free PMC article.

4

High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.

Chavan TS, Jang H, Khavrutskii L, Abraham SJ, Banerjee A, Freed BC, Johannessen L, Tarasov SG, Gaponenko V, Nussinov R, Tarasova NI. Chavan TS, et al. Among authors: gaponenko v. Biophys J. 2015 Dec 15;109(12):2602-2613. doi: 10.1016/j.bpj.2015.09.034. Biophys J. 2015. PMID: 26682817 Free PMC article.

5

The structure of monomeric components of self-assembling CXCR4 antagonists determines the architecture of resulting nanostructures.

Lee Y, Chen Y, Tarasova NI, Gaponenko V. Lee Y, et al. Among authors: gaponenko v. Nanotechnology. 2011 Dec 16;22(50):505101. doi: 10.1088/0957-4484/22/50/505101. Epub 2011 Nov 23. Nanotechnology. 2011. PMID: 22107755 Free PMC article.

6

Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.

Jang H, Abraham SJ, Chavan TS, Hitchinson B, Khavrutskii L, Tarasova NI, Nussinov R, Gaponenko V. Jang H, et al. Among authors: gaponenko v. J Biol Chem. 2015 Apr 10;290(15):9465-77. doi: 10.1074/jbc.M114.620724. Epub 2015 Feb 24. J Biol Chem. 2015. PMID: 25713064 Free PMC article.

7

Novel peptide nanoparticle-biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness.

Grozdanovic M, Laffey KG, Abdelkarim H, Hitchinson B, Harijith A, Moon HG, Park GY, Rousslang LK, Masterson JC, Furuta GT, Tarasova NI, Gaponenko V, Ackerman SJ. Grozdanovic M, et al. Among authors: gaponenko v. J Allergy Clin Immunol. 2019 Feb;143(2):669-680.e12. doi: 10.1016/j.jaci.2018.05.003. Epub 2018 May 17. J Allergy Clin Immunol. 2019. PMID: 29778505 Free PMC article.

8

GTP-Dependent K-Ras Dimerization.

Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R. Muratcioglu S, et al. Among authors: gaponenko v. Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4. Structure. 2015. PMID: 26051715 Free PMC article.

9

Heteromerization of chemokine (C-X-C motif) receptor 4 with α1A/B-adrenergic receptors controls α1-adrenergic receptor function.

Tripathi A, Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, Volkman BF, Gaponenko V, Majetschak M. Tripathi A, et al. Among authors: gaponenko v. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1659-68. doi: 10.1073/pnas.1417564112. Epub 2015 Mar 16. Proc Natl Acad Sci U S A. 2015. PMID: 25775528 Free PMC article.

10

Biased antagonism of CXCR4 avoids antagonist tolerance.

Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI, Gaponenko V. Hitchinson B, et al. Among authors: gaponenko v. Sci Signal. 2018 Oct 16;11(552):eaat2214. doi: 10.1126/scisignal.aat2214. Sci Signal. 2018. PMID: 30327409 Free PMC article.

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