Lockett SJ - Search Results

1

Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target.

Timofeeva OA, Gaponenko V, Lockett SJ, Tarasov SG, Jiang S, Michejda CJ, Perantoni AO, Tarasova NI. Timofeeva OA, et al. Among authors: lockett sj. ACS Chem Biol. 2007 Dec 21;2(12):799-809. doi: 10.1021/cb700186x. ACS Chem Biol. 2007. PMID: 18154267

2

Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin.

Yan Q, Cho E, Lockett S, Muegge K. Yan Q, et al. Mol Cell Biol. 2003 Dec;23(23):8416-28. doi: 10.1128/MCB.23.23.8416-8428.2003. Mol Cell Biol. 2003. PMID: 14612388 Free PMC article.

3

The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation.

Song C, Xiao Z, Nagashima K, Li CC, Lockett SJ, Dai RM, Cho EH, Conrads TP, Veenstra TD, Colburn NH, Wang Q, Wang JM. Song C, et al. Among authors: lockett sj. Toxicol Appl Pharmacol. 2008 May 1;228(3):351-63. doi: 10.1016/j.taap.2007.12.026. Epub 2008 Jan 8. Toxicol Appl Pharmacol. 2008. PMID: 18261755 Free PMC article.

4

Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors.

Khan T, Stauffer JK, Williams R, Hixon JA, Salcedo R, Lincoln E, Back TC, Powell D, Lockett S, Arnold AC, Sayers TJ, Wigginton JM. Khan T, et al. J Immunol. 2006 May 15;176(10):6302-12. doi: 10.4049/jimmunol.176.10.6302. J Immunol. 2006. PMID: 16670342

5

Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma.

Khan T, Hixon JA, Stauffer JK, Lincoln E, Back TC, Brenner J, Lockett S, Nagashima K, Powell D, Wigginton JM. Khan T, et al. J Natl Cancer Inst. 2006 Feb 1;98(3):190-202. doi: 10.1093/jnci/djj021. J Natl Cancer Inst. 2006. PMID: 16449679

6

Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.

Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM. Turbyville TJ, et al. Among authors: lockett sj. Mol Cancer Ther. 2010 May;9(5):1234-43. doi: 10.1158/1535-7163.MCT-09-0834. Epub 2010 May 4. Mol Cancer Ther. 2010. PMID: 20442305 Free PMC article.

7

Photoinducible Oncometabolite Detection.

Kulkarni RA, Briney CA, Crooks DR, Bergholtz SE, Mushti C, Lockett SJ, Lane AN, Fan TW, Swenson RE, Marston Linehan W, Meier JL. Kulkarni RA, et al. Among authors: lockett sj. Chembiochem. 2019 Feb 1;20(3):360-365. doi: 10.1002/cbic.201800651. Epub 2018 Dec 13. Chembiochem. 2019. PMID: 30358041 Free PMC article.

8

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation.

Matarlo JS, Krumpe LRH, Heinz WF, Oh D, Shenoy SR, Thomas CL, Goncharova EI, Lockett SJ, O'Keefe BR. Matarlo JS, et al. Among authors: lockett sj. Cell Chem Biol. 2019 Aug 15;26(8):1133-1142.e4. doi: 10.1016/j.chembiol.2019.04.011. Epub 2019 May 30. Cell Chem Biol. 2019. PMID: 31155509 Free PMC article.

9

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation.

Yang HS, Jansen AP, Komar AA, Zheng X, Merrick WC, Costes S, Lockett SJ, Sonenberg N, Colburn NH. Yang HS, et al. Among authors: lockett sj. Mol Cell Biol. 2003 Jan;23(1):26-37. doi: 10.1128/MCB.23.1.26-37.2003. Mol Cell Biol. 2003. PMID: 12482958 Free PMC article.

10

CpG-containing oligodeoxynucleotide promotes microglial cell uptake of amyloid beta 1-42 peptide by up-regulating the expression of the G-protein- coupled receptor mFPR2.

Iribarren P, Chen K, Hu J, Gong W, Cho EH, Lockett S, Uranchimeg B, Wang JM. Iribarren P, et al. FASEB J. 2005 Dec;19(14):2032-4. doi: 10.1096/fj.05-4578fje. Epub 2005 Oct 11. FASEB J. 2005. PMID: 16219804

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