Huang LJ - Search Results

1

Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F.

Lu X, Huang LJ, Lodish HF. Lu X, et al. Among authors: huang lj. J Biol Chem. 2008 Feb 29;283(9):5258-66. doi: 10.1074/jbc.M707125200. Epub 2007 Dec 23. J Biol Chem. 2008. PMID: 18158285 Free article.

2

The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms.

Tong W, Sulahian R, Gross AW, Hendon N, Lodish HF, Huang LJ. Tong W, et al. Among authors: huang lj. J Biol Chem. 2006 Dec 15;281(50):38930-40. doi: 10.1074/jbc.M607524200. Epub 2006 Oct 19. J Biol Chem. 2006. PMID: 17052978 Free article.

3

A JAK2 interdomain linker relays Epo receptor engagement signals to kinase activation.

Zhao L, Dong H, Zhang CC, Kinch L, Osawa M, Iacovino M, Grishin NV, Kyba M, Huang LJ. Zhao L, et al. Among authors: huang lj. J Biol Chem. 2009 Sep 25;284(39):26988-98. doi: 10.1074/jbc.M109.011387. Epub 2009 Jul 28. J Biol Chem. 2009. PMID: 19638629 Free PMC article.

4

Ubiquitination regulates the internalization, endolysosomal sorting, and signaling of the erythropoietin receptor.

Bulut GB, Sulahian R, Ma Y, Chi NW, Huang LJ. Bulut GB, et al. Among authors: huang lj. J Biol Chem. 2011 Feb 25;286(8):6449-57. doi: 10.1074/jbc.M110.186890. Epub 2010 Dec 23. J Biol Chem. 2011. PMID: 21183685 Free PMC article.

5

Activating JAK2 mutants reveal cytokine receptor coupling differences that impact outcomes in myeloproliferative neoplasm.

Yao H, Ma Y, Hong Z, Zhao L, Monaghan SA, Hu MC, Huang LJ. Yao H, et al. Among authors: huang lj. Leukemia. 2017 Oct;31(10):2122-2131. doi: 10.1038/leu.2017.1. Epub 2017 Jan 6. Leukemia. 2017. PMID: 28057939 Free PMC article.

6

A regulating role of the JAK2 FERM domain in hyperactivation of JAK2(V617F).

Zhao L, Ma Y, Seemann J, Huang LJ. Zhao L, et al. Among authors: huang lj. Biochem J. 2010 Jan 27;426(1):91-8. doi: 10.1042/BJ20090615. Biochem J. 2010. PMID: 19929856 Free PMC article.

7

Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia.

Sulahian R, Cleaver O, Huang LJ. Sulahian R, et al. Among authors: huang lj. Blood. 2009 May 21;113(21):5287-97. doi: 10.1182/blood-2008-09-179572. Epub 2009 Mar 31. Blood. 2009. PMID: 19336760 Free PMC article.

8

Erythropoietin regulation of red blood cell production: from bench to bedside and back.

Bhoopalan SV, Huang LJ, Weiss MJ. Bhoopalan SV, et al. Among authors: huang lj. F1000Res. 2020 Sep 18;9:F1000 Faculty Rev-1153. doi: 10.12688/f1000research.26648.1. eCollection 2020. F1000Res. 2020. PMID: 32983414 Free PMC article. Review.

9

Advances in understanding the pathogenesis of primary familial and congenital polycythaemia.

Huang LJ, Shen YM, Bulut GB. Huang LJ, et al. Br J Haematol. 2010 Mar;148(6):844-52. doi: 10.1111/j.1365-2141.2009.08069.x. Epub 2010 Jan 20. Br J Haematol. 2010. PMID: 20096014 Free PMC article. Review.

10

Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.

Bulut GB, Sulahian R, Yao H, Huang LJ. Bulut GB, et al. Among authors: huang lj. Blood. 2013 Dec 5;122(24):3964-72. doi: 10.1182/blood-2013-05-506212. Epub 2013 Oct 10. Blood. 2013. PMID: 24113870 Free PMC article.

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