Mellaerts R - Search Results

1

Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.

Mellaerts R, Mols R, Jammaer JA, Aerts CA, Annaert P, Van Humbeeck J, Van den Mooter G, Augustijns P, Martens JA. Mellaerts R, et al. Eur J Pharm Biopharm. 2008 May;69(1):223-30. doi: 10.1016/j.ejpb.2007.11.006. Epub 2007 Nov 23. Eur J Pharm Biopharm. 2008. PMID: 18164930

2

Potential of amorphous microporous silica for ibuprofen controlled release.

Aerts CA, Verraedt E, Depla A, Follens L, Froyen L, Van Humbeeck J, Augustijns P, Van den Mooter G, Mellaerts R, Martens JA. Aerts CA, et al. Among authors: mellaerts r. Int J Pharm. 2010 Sep 15;397(1-2):84-91. doi: 10.1016/j.ijpharm.2010.06.053. Epub 2010 Jul 7. Int J Pharm. 2010. PMID: 20619331

3

Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials.

Mellaerts R, Aerts CA, Van Humbeeck J, Augustijns P, Van den Mooter G, Martens JA. Mellaerts R, et al. Chem Commun (Camb). 2007 Apr 7;(13):1375-7. doi: 10.1039/b616746b. Epub 2007 Jan 29. Chem Commun (Camb). 2007. PMID: 17377687

4

Ordered mesoporous silica induces pH-independent supersaturation of the basic low solubility compound itraconazole resulting in enhanced transepithelial transport.

Mellaerts R, Mols R, Kayaert P, Annaert P, Van Humbeeck J, Van den Mooter G, Martens JA, Augustijns P. Mellaerts R, et al. Int J Pharm. 2008 Jun 5;357(1-2):169-79. doi: 10.1016/j.ijpharm.2008.01.049. Epub 2008 Feb 3. Int J Pharm. 2008. PMID: 18325700

5

Physical state of poorly water soluble therapeutic molecules loaded into SBA-15 ordered mesoporous silica carriers: a case study with itraconazole and ibuprofen.

Mellaerts R, Jammaer JA, Van Speybroeck M, Chen H, Van Humbeeck J, Augustijns P, Van den Mooter G, Martens JA. Mellaerts R, et al. Langmuir. 2008 Aug 19;24(16):8651-9. doi: 10.1021/la801161g. Epub 2008 Jul 17. Langmuir. 2008. PMID: 18630936

6

Ordered mesoporous silica material SBA-15: a broad-spectrum formulation platform for poorly soluble drugs.

Van Speybroeck M, Barillaro V, Thi TD, Mellaerts R, Martens J, Van Humbeeck J, Vermant J, Annaert P, Van den Mooter G, Augustijns P. Van Speybroeck M, et al. Among authors: mellaerts r. J Pharm Sci. 2009 Aug;98(8):2648-58. doi: 10.1002/jps.21638. J Pharm Sci. 2009. PMID: 19072861

7

Growth of itraconazole nanofibers in supersaturated simulated intestinal fluid.

Mellaerts R, Aerts A, Caremans TP, Vermant J, Van den Mooter G, Martens JA, Augustijns P. Mellaerts R, et al. Mol Pharm. 2010 Jun 7;7(3):905-13. doi: 10.1021/mp900300j. Mol Pharm. 2010. PMID: 20232903

8

Combined use of ordered mesoporous silica and precipitation inhibitors for improved oral absorption of the poorly soluble weak base itraconazole.

Van Speybroeck M, Mols R, Mellaerts R, Thi TD, Martens JA, Van Humbeeck J, Annaert P, Van den Mooter G, Augustijns P. Van Speybroeck M, et al. Among authors: mellaerts r. Eur J Pharm Biopharm. 2010 Aug;75(3):354-65. doi: 10.1016/j.ejpb.2010.04.009. Epub 2010 Apr 24. Eur J Pharm Biopharm. 2010. PMID: 20420905

9

Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica.

Van Speybroeck M, Mellaerts R, Mols R, Thi TD, Martens JA, Van Humbeeck J, Annaert P, Van den Mooter G, Augustijns P. Van Speybroeck M, et al. Among authors: mellaerts r. Eur J Pharm Sci. 2010 Dec 23;41(5):623-30. doi: 10.1016/j.ejps.2010.09.002. Epub 2010 Sep 17. Eur J Pharm Sci. 2010. PMID: 20850527

10

Molecular organization of hydrophobic molecules and co-adsorbed water in SBA-15 ordered mesoporous silica material.

Mellaerts R, Roeffaers MB, Houthoofd K, Van Speybroeck M, De Cremer G, Jammaer JA, Van den Mooter G, Augustijns P, Hofkens J, Martens JA. Mellaerts R, et al. Phys Chem Chem Phys. 2011 Feb 21;13(7):2706-13. doi: 10.1039/c0cp01640c. Epub 2010 Dec 10. Phys Chem Chem Phys. 2011. PMID: 21152589

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