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Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.
Pratama A, Ramiscal RR, Silva DG, Das SK, Athanasopoulos V, Fitch J, Botelho NK, Chang PP, Hu X, Hogan JJ, Maña P, Bernal D, Korner H, Yu D, Goodnow CC, Cook MC, Vinuesa CG. Pratama A, et al. Among authors: hu x. Immunity. 2013 Apr 18;38(4):669-80. doi: 10.1016/j.immuni.2013.01.011. Epub 2013 Apr 11. Immunity. 2013. PMID: 23583642 Free article.
Heterozygosity for Roquinsan leads to angioimmunoblastic T-cell lymphoma-like tumors in mice.
Ellyard JI, Chia T, Rodriguez-Pinilla SM, Martin JL, Hu X, Navarro-Gonzalez M, Garcia JF, Delfau-Larue MH, Montes-Moreno S, Gaulard P, Cook MC, Walters G, Piris MA, Vinuesa CG. Ellyard JI, et al. Among authors: hu x. Blood. 2012 Jul 26;120(4):812-21. doi: 10.1182/blood-2011-07-365130. Epub 2012 Jun 13. Blood. 2012. PMID: 22700722 Free article.
Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, Ghali JR, Cook MC, Riminton DS, Veillette A, Schwartzberg PL, Mackay F, Brink R, Tangye SG, Vinuesa CG, Mackay CR, Li Z, Yu D. He J, et al. Among authors: hu x. Immunity. 2013 Oct 17;39(4):770-81. doi: 10.1016/j.immuni.2013.09.007. Immunity. 2013. PMID: 24138884 Free article.
Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
He J, Zhang X, Wei Y, Sun X, Chen Y, Deng J, Jin Y, Gan Y, Hu X, Jia R, Xu C, Hou Z, Leong YA, Zhu L, Feng J, An Y, Jia Y, Li C, Liu X, Ye H, Ren L, Li R, Yao H, Li Y, Chen S, Zhang X, Su Y, Guo J, Shen N, Morand EF, Yu D, Li Z. He J, et al. Among authors: hu x. Nat Med. 2016 Sep;22(9):991-3. doi: 10.1038/nm.4148. Epub 2016 Aug 8. Nat Med. 2016. PMID: 27500725
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