Kosinski A - Search Results

1

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: kosinski a. J Med Chem. 2008 Feb 14;51(3):545-52. doi: 10.1021/jm070760l. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173229

2

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB.

Mallari JP, Shelat A, Kosinski A, Caffrey CR, Connelly M, Zhu F, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: kosinski a. Bioorg Med Chem Lett. 2008 May 1;18(9):2883-5. doi: 10.1016/j.bmcl.2008.03.083. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18420405 Free PMC article.

3

Structure-guided development of selective TbcatB inhibitors.

Mallari JP, Shelat AA, Kosinski A, Caffrey CR, Connelly M, Zhu F, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: kosinski a. J Med Chem. 2009 Oct 22;52(20):6489-93. doi: 10.1021/jm900908p. J Med Chem. 2009. PMID: 19769357 Free PMC article.

4

Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

Arnold LA, Kosinski A, Estébanez-Perpiñá E, Fletterick RJ, Guy RK. Arnold LA, et al. Among authors: kosinski a. J Med Chem. 2007 Nov 1;50(22):5269-80. doi: 10.1021/jm070556y. Epub 2007 Oct 5. J Med Chem. 2007. PMID: 17918822 Free PMC article.

5

Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.

Hwang JY, Arnold LA, Zhu F, Kosinski A, Mangano TJ, Setola V, Roth BL, Guy RK. Hwang JY, et al. Among authors: kosinski a. J Med Chem. 2009 Jul 9;52(13):3892-901. doi: 10.1021/jm9002704. J Med Chem. 2009. PMID: 19469546 Free PMC article.

6

Novel flufenamic acid analogues as inhibitors of androgen receptor mediated transcription.

Féau C, Arnold LA, Kosinski A, Zhu F, Connelly M, Guy RK. Féau C, et al. Among authors: kosinski a. ACS Chem Biol. 2009 Oct 16;4(10):834-43. doi: 10.1021/cb900143a. ACS Chem Biol. 2009. PMID: 19645433 Free PMC article.

7

A high-throughput ligand competition binding assay for the androgen receptor and other nuclear receptors.

Féau C, Arnold LA, Kosinski A, Guy RK. Féau C, et al. Among authors: kosinski a. J Biomol Screen. 2009 Jan;14(1):43-8. doi: 10.1177/1087057108326662. J Biomol Screen. 2009. PMID: 19171919 Free PMC article.

8

Ligand competition binding assay for the androgen receptor.

Féau C, Arnold LA, Kosinski A, Guy RK. Féau C, et al. Among authors: kosinski a. Methods Mol Biol. 2011;776:59-68. doi: 10.1007/978-1-61779-243-4_4. Methods Mol Biol. 2011. PMID: 21796520

9

Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin.

Partridge JF, DeBeauchamp JL, Kosinski AM, Ulrich DL, Hadler MJ, Noffsinger VJ. Partridge JF, et al. Mol Cell. 2007 May 25;26(4):593-602. doi: 10.1016/j.molcel.2007.05.004. Mol Cell. 2007. PMID: 17531816 Free article.

10

Chp1-Tas3 interaction is required to recruit RITS to fission yeast centromeres and for maintenance of centromeric heterochromatin.

Debeauchamp JL, Moses A, Noffsinger VJ, Ulrich DL, Job G, Kosinski AM, Partridge JF. Debeauchamp JL, et al. Among authors: kosinski am. Mol Cell Biol. 2008 Apr;28(7):2154-66. doi: 10.1128/MCB.01637-07. Epub 2008 Jan 22. Mol Cell Biol. 2008. PMID: 18212052 Free PMC article.

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