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Heritability and genome-wide linkage in US and australian twins identify novel genomic regions controlling chromogranin a: implications for secretion and blood pressure.
O'Connor DT, Zhu G, Rao F, Taupenot L, Fung MM, Das M, Mahata SK, Mahata M, Wang L, Zhang K, Greenwood TA, Shih PA, Cockburn MG, Ziegler MG, Stridsberg M, Martin NG, Whitfield JB. O'Connor DT, et al. Among authors: fung mm. Circulation. 2008 Jul 15;118(3):247-57. doi: 10.1161/CIRCULATIONAHA.107.709105. Epub 2008 Jun 30. Circulation. 2008. PMID: 18591442 Free PMC article.
Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.
Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, Taupenot L, O'Connor DT. Chen Y, et al. Among authors: fung mm. J Am Coll Cardiol. 2008 Oct 28;52(18):1468-81. doi: 10.1016/j.jacc.2008.07.047. J Am Coll Cardiol. 2008. PMID: 19017515 Free PMC article.
Autonomic function in hypertension; role of genetic variation at the catecholamine storage vesicle protein chromogranin B.
Zhang K, Rao F, Rana BK, Gayen JR, Calegari F, King A, Rosa P, Huttner WB, Stridsberg M, Mahata M, Vaingankar S, Mahboubi V, Salem RM, Rodriguez-Flores JL, Fung MM, Smith DW, Schork NJ, Ziegler MG, Taupenot L, Mahata SK, O'Connor DT. Zhang K, et al. Among authors: fung mm. Circ Cardiovasc Genet. 2009 Feb;2(1):46-56. doi: 10.1161/CIRCGENETICS.108.785659. Circ Cardiovasc Genet. 2009. PMID: 20011129 Free PMC article.
Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertension.
Zhang K, Rao F, Wang L, Rana BK, Ghosh S, Mahata M, Salem RM, Rodriguez-Flores JL, Fung MM, Waalen J, Tayo B, Taupenot L, Mahata SK, O'Connor DT. Zhang K, et al. Among authors: fung mm. J Am Coll Cardiol. 2010 Apr 6;55(14):1463-75. doi: 10.1016/j.jacc.2009.11.064. J Am Coll Cardiol. 2010. PMID: 20359597 Free PMC article.
Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.
Rao F, Chiron S, Wei Z, Fung MM, Chen Y, Wen G, Khandrika S, Ziegler MG, Benyamin B, Montgomery G, Whitfield JB, Martin NG, Waalen J, Hamilton BA, Mahata SK, O'Connor DT. Rao F, et al. Among authors: fung mm. Am J Hypertens. 2012 Jan;25(1):29-40. doi: 10.1038/ajh.2011.163. Epub 2011 Sep 15. Am J Hypertens. 2012. PMID: 21918574 Free PMC article.
Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses.
Zhang K, Rao F, Miramontes-Gonzalez JP, Hightower CM, Vaught B, Chen Y, Greenwood TA, Schork AJ, Wang L, Mahata M, Stridsberg M, Khandrika S, Biswas N, Fung MM, Waalen J, Middelberg RP, Heath AC, Montgomery GW, Martin NG, Whitfield JB, Baker DG, Schork NJ, Nievergelt CM, O'Connor DT. Zhang K, et al. Among authors: fung mm. J Am Coll Cardiol. 2012 Oct 23;60(17):1678-89. doi: 10.1016/j.jacc.2012.06.042. Epub 2012 Sep 26. J Am Coll Cardiol. 2012. PMID: 23021333 Free PMC article.
Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].
Zhang K, Deacon DC, Rao F, Schork AJ, Fung MM, Waalen J, Schork NJ, Nievergelt CM, Chi NC, O'Connor DT. Zhang K, et al. Among authors: fung mm. J Am Coll Cardiol. 2014 Feb 4;63(4):358-68. doi: 10.1016/j.jacc.2013.09.025. Epub 2013 Oct 16. J Am Coll Cardiol. 2014. PMID: 24140660 Free PMC article.
Chromogranin A regulates renal function by triggering Weibel-Palade body exocytosis.
Chen Y, Mahata M, Rao F, Khandrika S, Courel M, Fung MM, Zhang K, Stridsberg M, Ziegler MG, Hamilton BA, Lipkowitz MS, Taupenot L, Nievergelt C, Mahata SK, O'Connor DT. Chen Y, et al. Among authors: fung mm. J Am Soc Nephrol. 2009 Jul;20(7):1623-32. doi: 10.1681/ASN.2008111148. Epub 2009 Jun 11. J Am Soc Nephrol. 2009. PMID: 19520754 Free PMC article.
77 results