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Non-charged thiamine analogs as inhibitors of enzyme transketolase.
Thomas AA, De Meese J, Le Huerou Y, Boyd SA, Romoff TT, Gonzales SS, Gunawardana I, Kaplan T, Sullivan F, Condroski K, Lyssikatos JP, Aicher TD, Ballard J, Bernat B, DeWolf W, Han M, Lemieux C, Smith D, Weiler S, Wright SK, Vigers G, Brandhuber B. Thomas AA, et al. Among authors: wright sk. Bioorg Med Chem Lett. 2008 Jan 15;18(2):509-12. doi: 10.1016/j.bmcl.2007.11.098. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18182286
Prodrug thiamine analogs as inhibitors of the enzyme transketolase.
Le Huerou Y, Gunawardana I, Thomas AA, Boyd SA, de Meese J, Dewolf W, Gonzales SS, Han M, Hayter L, Kaplan T, Lemieux C, Lee P, Pheneger J, Poch G, Romoff TT, Sullivan F, Weiler S, Wright SK, Lin J. Le Huerou Y, et al. Among authors: wright sk. Bioorg Med Chem Lett. 2008 Jan 15;18(2):505-8. doi: 10.1016/j.bmcl.2007.11.100. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18083562
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.
Thomas AA, Le Huerou Y, De Meese J, Gunawardana I, Kaplan T, Romoff TT, Gonzales SS, Condroski K, Boyd SA, Ballard J, Bernat B, DeWolf W, Han M, Lee P, Lemieux C, Pedersen R, Pheneger J, Poch G, Smith D, Sullivan F, Weiler S, Wright SK, Lin J, Brandhuber B, Vigers G. Thomas AA, et al. Among authors: wright sk. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2206-10. doi: 10.1016/j.bmcl.2007.11.101. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18267359
NORSE/FIRES: how can we advance our understanding of this devastating condition?
Champsas D, Zhang X, Rosch R, Ioannidou E, Gilmour K, Cooray G, Woodhall G, Pujar S, Kaliakatsos M, Wright SK. Champsas D, et al. Among authors: wright sk. Front Neurol. 2024 Aug 8;15:1426051. doi: 10.3389/fneur.2024.1426051. eCollection 2024. Front Neurol. 2024. PMID: 39175762 Free PMC article. Review.
Human cerebrospinal fluid monoclonal CASPR2 autoantibodies induce changes in electrophysiology, functional MRI, and behavior in rodent models.
van Hoof S, Kreye J, Cordero-Gómez C, Hoffmann J, Momsen Reincke S, Sánchez-Sendin E, Duong SL, Upadhya M, Dhangar D, Michór P, Woodhall GL, Küpper M, Oder A, Kuchling J, Koch SP, Mueller S, Boehm-Sturm P, von Kries JP, Finke C, Kirschstein T, Wright SK, Prüss H. van Hoof S, et al. Among authors: wright sk. Brain Behav Immun. 2024 Nov;122:266-278. doi: 10.1016/j.bbi.2024.08.027. Epub 2024 Aug 13. Brain Behav Immun. 2024. PMID: 39142424 Free article.
56 results