Clynes M - Search Results

1

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.

Martinez VG, Williams KJ, Stratford IJ, Clynes M, O'Connor R. Martinez VG, et al. Among authors: clynes m. Toxicol In Vitro. 2008 Apr;22(3):582-8. doi: 10.1016/j.tiv.2007.11.017. Epub 2007 Dec 7. Toxicol In Vitro. 2008. PMID: 18191533

2

Recent developments in drug resistance and apoptosis research.

Clynes M, Daly C, NicAmhlaoibh R, Cronin D, Elliott C, O'Connor R, O'Doherty T, Connolly L, Howlett A, Scanlon K. Clynes M, et al. Crit Rev Oncol Hematol. 1998 Sep;28(3):181-205. doi: 10.1016/s1040-8428(98)00018-3. Crit Rev Oncol Hematol. 1998. PMID: 9793746 Review. No abstract available.

3

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).

Duffy CP, Elliott CJ, O'Connor RA, Heenan MM, Coyle S, Cleary IM, Kavanagh K, Verhaegen S, O'Loughlin CM, NicAmhlaoibh R, Clynes M. Duffy CP, et al. Among authors: clynes m. Eur J Cancer. 1998 Jul;34(8):1250-9. doi: 10.1016/s0959-8049(98)00045-8. Eur J Cancer. 1998. PMID: 9849488

4

Synthesis of indomethacin analogues for evaluation as modulators of MRP activity.

Maguire AR, Plunkett SJ, Papot S, Clynes M, O'Connor R, Touhey S. Maguire AR, et al. Among authors: clynes m. Bioorg Med Chem. 2001 Mar;9(3):745-62. doi: 10.1016/s0968-0896(00)00292-3. Bioorg Med Chem. 2001. PMID: 11310610

5

Structure-activity relationship of indomethacin analogues for MRP-1, COX-1 and COX-2 inhibition. identification of novel chemotherapeutic drug resistance modulators.

Touhey S, O'Connor R, Plunkett S, Maguire A, Clynes M. Touhey S, et al. Among authors: clynes m. Eur J Cancer. 2002 Aug;38(12):1661-70. doi: 10.1016/s0959-8049(02)00128-4. Eur J Cancer. 2002. PMID: 12142058

6

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.

Moran E, O'Keeffe M, O'Connor R, Larkin AM, Murphy P, Clynes M. Moran E, et al. Among authors: clynes m. J Immunol Methods. 2002 Dec 20;271(1-2):65-75. doi: 10.1016/s0022-1759(02)00340-x. J Immunol Methods. 2002. PMID: 12445730

7

Challenges in molecular analysis for individualized cancer therapy.

Clynes M, O'Connor R, O'Driscoll L, Daly C, Meleady P. Clynes M, et al. Drug Discov Today. 2003 Jun 15;8(12):531. doi: 10.1016/s1359-6446(03)02730-2. Drug Discov Today. 2003. PMID: 12821298 No abstract available.

8

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes.

Coyle B, Kinsella P, McCann M, Devereux M, O'Connor R, Clynes M, Kavanagh K. Coyle B, et al. Among authors: clynes m. Toxicol In Vitro. 2004 Feb;18(1):63-70. doi: 10.1016/j.tiv.2003.08.011. Toxicol In Vitro. 2004. PMID: 14630063

9

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.

O'Connor R, Heenan M, Connolly L, Larkin A, Clynes M. O'Connor R, et al. Among authors: clynes m. Anticancer Res. 2004 Mar-Apr;24(2A):457-64. Anticancer Res. 2004. PMID: 15152944 Free article.

10

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.

Liang Y, O'Driscoll L, McDonnell S, Doolan P, Oglesby I, Duffy K, O'Connor R, Clynes M. Liang Y, et al. Among authors: clynes m. Int J Cancer. 2004 Sep 10;111(4):484-93. doi: 10.1002/ijc.20230. Int J Cancer. 2004. PMID: 15239124

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