Shatkin AJ - Search Results

1

High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.

Das K, Bauman JD, Clark AD Jr, Frenkel YV, Lewi PJ, Shatkin AJ, Hughes SH, Arnold E. Das K, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1466-71. doi: 10.1073/pnas.0711209105. Epub 2008 Jan 29. Proc Natl Acad Sci U S A. 2008. PMID: 18230722 Free PMC article.

2

Structure of the guanylyltransferase domain of human mRNA capping enzyme.

Chu C, Das K, Tyminski JR, Bauman JD, Guan R, Qiu W, Montelione GT, Arnold E, Shatkin AJ. Chu C, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10104-8. doi: 10.1073/pnas.1106610108. Epub 2011 Jun 2. Proc Natl Acad Sci U S A. 2011. PMID: 21636784 Free PMC article.

3

Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening.

Bauman JD, Patel D, Dharia C, Fromer MW, Ahmed S, Frenkel Y, Vijayan RS, Eck JT, Ho WC, Das K, Shatkin AJ, Arnold E. Bauman JD, et al. Among authors: shatkin aj. J Med Chem. 2013 Apr 11;56(7):2738-46. doi: 10.1021/jm301271j. Epub 2013 Feb 20. J Med Chem. 2013. PMID: 23342998 Free PMC article.

4

Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design.

Bauman JD, Das K, Ho WC, Baweja M, Himmel DM, Clark AD Jr, Oren DA, Boyer PL, Hughes SH, Shatkin AJ, Arnold E. Bauman JD, et al. Among authors: shatkin aj. Nucleic Acids Res. 2008 Sep;36(15):5083-92. doi: 10.1093/nar/gkn464. Epub 2008 Aug 1. Nucleic Acids Res. 2008. PMID: 18676450 Free PMC article.

5

3D jigsaw puzzle in rotavirus assembly.

Shatkin A, Das K, Arnold E. Shatkin A, et al. Structure. 2008 Nov 12;16(11):1601-2. doi: 10.1016/j.str.2008.10.004. Structure. 2008. PMID: 19000811 Free article.

6

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II.

Yue Z, Maldonado E, Pillutla R, Cho H, Reinberg D, Shatkin AJ. Yue Z, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12898-903. doi: 10.1073/pnas.94.24.12898. Proc Natl Acad Sci U S A. 1997. PMID: 9371772 Free PMC article.

7

Translation of bicistronic viral mRNA in transfected cells: regulation at the level of elongation.

Fajardo JE, Shatkin AJ. Fajardo JE, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 1990 Jan;87(1):328-32. doi: 10.1073/pnas.87.1.328. Proc Natl Acad Sci U S A. 1990. PMID: 2296589 Free PMC article.

8

Avian reovirus mRNAs are nonfunctional in infected mouse cells: translational basis for virus host-range restriction.

Benavente J, Shatkin AJ. Benavente J, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 1988 Jun;85(12):4257-61. doi: 10.1073/pnas.85.12.4257. Proc Natl Acad Sci U S A. 1988. PMID: 3380790 Free PMC article.

9

Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism.

Wen Y, Yue Z, Shatkin AJ. Wen Y, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12226-31. doi: 10.1073/pnas.95.21.12226. Proc Natl Acad Sci U S A. 1998. PMID: 9770468 Free PMC article.

10

Escherichia coli kgtP encodes an alpha-ketoglutarate transporter.

Seol W, Shatkin AJ. Seol W, et al. Among authors: shatkin aj. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3802-6. doi: 10.1073/pnas.88.9.3802. Proc Natl Acad Sci U S A. 1991. PMID: 2053984 Free PMC article.

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