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Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor.
Wang J, Tucker LA, Stavropoulos J, Zhang Q, Wang YC, Bukofzer G, Niquette A, Meulbroek JA, Barnes DM, Shen J, Bouska J, Donawho C, Sheppard GS, Bell RL. Wang J, et al. Among authors: niquette a. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1838-43. doi: 10.1073/pnas.0708766105. Epub 2008 Feb 5. Proc Natl Acad Sci U S A. 2008. PMID: 18252827 Free PMC article.
ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors.
Palma JP, Wang YC, Rodriguez LE, Montgomery D, Ellis PA, Bukofzer G, Niquette A, Liu X, Shi Y, Lasko L, Zhu GD, Penning TD, Giranda VL, Rosenberg SH, Frost DJ, Donawho CK. Palma JP, et al. Among authors: niquette a. Clin Cancer Res. 2009 Dec 1;15(23):7277-90. doi: 10.1158/1078-0432.CCR-09-1245. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934293
Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor.
Albert DH, Tapang P, Magoc TJ, Pease LJ, Reuter DR, Wei RQ, Li J, Guo J, Bousquet PF, Ghoreishi-Haack NS, Wang B, Bukofzer GT, Wang YC, Stavropoulos JA, Hartandi K, Niquette AL, Soni N, Johnson EF, McCall JO, Bouska JJ, Luo Y, Donawho CK, Dai Y, Marcotte PA, Glaser KB, Michaelides MR, Davidsen SK. Albert DH, et al. Among authors: niquette al. Mol Cancer Ther. 2006 Apr;5(4):995-1006. doi: 10.1158/1535-7163.MCT-05-0410. Mol Cancer Ther. 2006. PMID: 16648571