Cheng H - Search Results

1

Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model.

Cao X, Jia G, Zhang T, Yang M, Wang B, Wassenaar PA, Cheng H, Knopp MV, Sun D. Cao X, et al. Among authors: cheng h. Cancer Chemother Pharmacol. 2008 Nov;62(6):985-94. doi: 10.1007/s00280-008-0688-8. Epub 2008 Feb 6. Cancer Chemother Pharmacol. 2008. PMID: 18253734

2

Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor.

Cao X, Bloomston M, Zhang T, Frankel WL, Jia G, Wang B, Hall NC, Koch RM, Cheng H, Knopp MV, Sun D. Cao X, et al. Among authors: cheng h. Clin Cancer Res. 2008 Mar 15;14(6):1831-9. doi: 10.1158/1078-0432.CCR-07-1607. Clin Cancer Res. 2008. PMID: 18347186

3

Synthesis and enzyme-specific activation of carbohydrate-geldanamycin conjugates with potent anticancer activity.

Cheng H, Cao X, Xian M, Fang L, Cai TB, Ji JJ, Tunac JB, Sun D, Wang PG. Cheng H, et al. J Med Chem. 2005 Jan 27;48(2):645-52. doi: 10.1021/jm049693a. J Med Chem. 2005. PMID: 15658879

4

Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.

Fang L, Battisti RF, Cheng H, Reigan P, Xin Y, Shen J, Ross D, Chan KK, Martin EW Jr, Wang PG, Sun D. Fang L, et al. Among authors: cheng h. J Med Chem. 2006 Oct 19;49(21):6290-7. doi: 10.1021/jm060647f. J Med Chem. 2006. PMID: 17034135 Free PMC article.

5

Syntheses and biological activities of disaccharide daunorubicins.

Zhang G, Fang L, Zhu L, Aimiuwu JE, Shen J, Cheng H, Muller MT, Lee GE, Sun D, Wang PG. Zhang G, et al. Among authors: cheng h. J Med Chem. 2005 Aug 11;48(16):5269-78. doi: 10.1021/jm050144u. J Med Chem. 2005. PMID: 16078845

6

Syntheses and biological activities of rebeccamycin analogues with uncommon sugars.

Zhang G, Shen J, Cheng H, Zhu L, Fang L, Luo S, Muller MT, Lee GE, Wei L, Du Y, Sun D, Wang PG. Zhang G, et al. Among authors: cheng h. J Med Chem. 2005 Apr 7;48(7):2600-11. doi: 10.1021/jm0493764. J Med Chem. 2005. PMID: 15801850

7

Phase I and pharmacokinetic study of erlotinib (OSI-774) in combination with docetaxel in squamous cell carcinoma of the head and neck (SSCHN).

Kraut EH, Rhoades C, Zhang Y, Cheng H, Aimiumu J, Chen P, Lang J, Young DC, Agrawal A, Dancey J, Chan KK, Grever MR. Kraut EH, et al. Among authors: cheng h. Cancer Chemother Pharmacol. 2011 Mar;67(3):579-86. doi: 10.1007/s00280-010-1332-y. Epub 2010 May 19. Cancer Chemother Pharmacol. 2011. PMID: 20490801 Free PMC article. Clinical Trial.

8

Enzyme kinetics of GTI-2040, a phosphorothioate oligonucleotide targeting ribonucleotide reductase.

Wei X, Dai G, Liu Z, Cheng H, Xie Z, Klisovic R, Marcucci G, Chan KK. Wei X, et al. Among authors: cheng h. Drug Metab Dispos. 2008 Nov;36(11):2227-33. doi: 10.1124/dmd.108.021295. Epub 2008 Jul 24. Drug Metab Dispos. 2008. PMID: 18653746 Clinical Trial.

9

Preclinical Pharmacokinetics Study of R- and S-Enantiomers of the Histone Deacetylase Inhibitor, AR-42 (NSC 731438), in Rodents.

Cheng H, Xie Z, Jones WP, Wei XT, Liu Z, Wang D, Kulp SK, Wang J, Coss CC, Chen CS, Marcucci G, Garzon R, Covey JM, Phelps MA, Chan KK. Cheng H, et al. AAPS J. 2016 May;18(3):737-45. doi: 10.1208/s12248-016-9876-3. Epub 2016 Mar 4. AAPS J. 2016. PMID: 26943915 Free PMC article.

10

Metabolism of GTI-2040, a phosphorothioate oligonucleotide antisense, using ion-pair reversed phase high performance liquid chromatography (HPLC) coupled with electrospray ion-trap mass spectrometry.

Wei X, Dai G, Liu Z, Cheng H, Xie Z, Marcucci G, Chan KK. Wei X, et al. Among authors: cheng h. AAPS J. 2006;8(4):E743-55. doi: 10.1208/aapsj080484. AAPS J. 2006. PMID: 17285740 Free PMC article.

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