Liu-Chen LY - Search Results

1

Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits.

Li JG, Lehr M, Liu-Chen LY, Woodruff-Pak DS. Li JG, et al. Neuropsychopharmacology. 2008 Nov;33(12):2820-30. doi: 10.1038/npp.2008.1. Epub 2008 Feb 6. Neuropsychopharmacology. 2008. PMID: 18256594

2

Molecular basis of differences in (-)(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl]benzeneacetamide-induced desensitization and phosphorylation between human and rat kappa-opioid receptors expressed in Chinese hamster ovary cells.

Li J, Li JG, Chen C, Zhang F, Liu-Chen LY. Li J, et al. Mol Pharmacol. 2002 Jan;61(1):73-84. doi: 10.1124/mol.61.1.73. Mol Pharmacol. 2002. PMID: 11752208

3

Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human kappa opioid receptor by enhancing its recycling rate.

Li JG, Chen C, Liu-Chen LY. Li JG, et al. J Biol Chem. 2002 Jul 26;277(30):27545-52. doi: 10.1074/jbc.M200058200. Epub 2002 May 9. J Biol Chem. 2002. PMID: 12004055 Free article.

4

(-)U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide] induces internalization and down-regulation of the human, but not the rat, kappa-opioid receptor: structural basis for the differential regulation.

Zhang F, Li J, Li JG, Liu-Chen LY. Zhang F, et al. J Pharmacol Exp Ther. 2002 Sep;302(3):1184-92. doi: 10.1124/jpet.302.3.1184. J Pharmacol Exp Ther. 2002. PMID: 12183679

5

Differential regulation of the human kappa opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation.

Li JG, Zhang F, Jin XL, Liu-Chen LY. Li JG, et al. J Pharmacol Exp Ther. 2003 May;305(2):531-40. doi: 10.1124/jpet.102.045559. Epub 2003 Jan 24. J Pharmacol Exp Ther. 2003. PMID: 12606694

6

Differential effects of agonists on adenylyl cyclase superactivation mediated by the kappa opioid receptors: adenylyl cyclase superactivation is independent of agonist-induced phosphorylation, desensitization, internalization, and down-regulation.

Wang Y, Li JG, Huang P, Xu W, Liu-Chen LY. Wang Y, et al. J Pharmacol Exp Ther. 2003 Dec;307(3):1127-34. doi: 10.1124/jpet.103.055814. Epub 2003 Oct 13. J Pharmacol Exp Ther. 2003. PMID: 14557376

7

kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins.

Huang P, Steplock D, Weinman EJ, Hall RA, Ding Z, Li J, Wang Y, Liu-Chen LY. Huang P, et al. J Biol Chem. 2004 Jun 11;279(24):25002-9. doi: 10.1074/jbc.M313366200. Epub 2004 Apr 7. J Biol Chem. 2004. PMID: 15070904 Free article.

8

Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.

Wang Y, Tang K, Inan S, Siebert D, Holzgrabe U, Lee DY, Huang P, Li JG, Cowan A, Liu-Chen LY. Wang Y, et al. J Pharmacol Exp Ther. 2005 Jan;312(1):220-30. doi: 10.1124/jpet.104.073668. Epub 2004 Sep 21. J Pharmacol Exp Ther. 2005. PMID: 15383632

9

GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.

Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY. Chen C, et al. J Biol Chem. 2006 Mar 24;281(12):7983-93. doi: 10.1074/jbc.M509805200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431922 Free article.

10

Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C(2) and substitution at C(18).

Béguin C, Richards MR, Li JG, Wang Y, Xu W, Liu-Chen LY, Carlezon WA Jr, Cohen BM. Béguin C, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4679-85. doi: 10.1016/j.bmcl.2006.05.093. Epub 2006 Jun 13. Bioorg Med Chem Lett. 2006. PMID: 16777411

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