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Page 1
Identification of CXCR3 receptor agonists in combinatorial small-molecule libraries.
Stroke IL, Cole AG, Simhadri S, Brescia MR, Desai M, Zhang JJ, Merritt JR, Appell KC, Henderson I, Webb ML. Stroke IL, et al. Among authors: appell kc. Biochem Biophys Res Commun. 2006 Oct 13;349(1):221-8. doi: 10.1016/j.bbrc.2006.08.019. Epub 2006 Aug 11. Biochem Biophys Res Commun. 2006. PMID: 16930533
Synthesis of (3,4-dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists.
Cole AG, Stroke IL, Qin LY, Hussain Z, Simhadri S, Brescia MR, Waksmunski FS, Strohl B, Tellew JE, Williams JP, Saunders J, Appell KC, Henderson I, Webb ML. Cole AG, et al. Among authors: appell kc. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5420-3. doi: 10.1016/j.bmcl.2008.09.038. Epub 2008 Sep 12. Bioorg Med Chem Lett. 2008. PMID: 18815029
Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.
Cole AG, Metzger A, Brescia MR, Qin LY, Appell KC, Brain CT, Hallett A, Ganju P, Denholm AA, Wareing JR, Ritchie TJ, Drake GM, Bevan SJ, MacGloinn A, McBryde A, Patel V, Oakley PJ, Nunez X, Gstach H, Schneider P, Baldwin JJ, Dolle RE, McDonald E, Henderson I. Cole AG, et al. Among authors: appell kc. Bioorg Med Chem Lett. 2009 Jan 1;19(1):119-22. doi: 10.1016/j.bmcl.2008.11.005. Epub 2008 Nov 6. Bioorg Med Chem Lett. 2009. PMID: 19014884
Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.
Merritt JR, Liu J, Quadros E, Morris ML, Liu R, Zhang R, Jacob B, Postelnek J, Hicks CM, Chen W, Kimble EF, Rogers WL, O'Brien L, White N, Desai H, Bansal S, King G, Ohlmeyer MJ, Appell KC, Webb ML. Merritt JR, et al. Among authors: appell kc. J Med Chem. 2009 Mar 12;52(5):1295-301. doi: 10.1021/jm801416q. J Med Chem. 2009. PMID: 19183043
2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.
Cole AG, Bohnstedt AC, Paradkar V, Kingsbury C, Quintero JG, Park H, Lu Y, You M, Neagu I, Diller DJ, Letourneau JJ, Shao Y, James RA, Riviello CM, Ho KK, Lin TH, Wang B, Appell KC, Sills M, Quadros E, Kimble EF, Ohlmeyer MH, Webb ML. Cole AG, et al. Among authors: appell kc. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6788-92. doi: 10.1016/j.bmcl.2009.09.080. Epub 2009 Sep 25. Bioorg Med Chem Lett. 2009. PMID: 19836234
Novel pyrrolidine heterocycles as CCR1 antagonists.
Merritt JR, James R, Paradkar VM, Zhang C, Liu R, Liu J, Jacob B, Chiriac C, Ohlmeyer MJ, Quadros E, Wines P, Postelnek J, Hicks CM, Chen W, Kimble EF, O'Brien L, White N, Desai H, Appell KC, Webb ML. Merritt JR, et al. Among authors: appell kc. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5477-9. doi: 10.1016/j.bmcl.2010.07.082. Epub 2010 Jul 24. Bioorg Med Chem Lett. 2010. PMID: 20708929
33 results