Cencic R - Search Results

1

Selective pharmacological targeting of a DEAD box RNA helicase.

Lindqvist L, Oberer M, Reibarkh M, Cencic R, Bordeleau ME, Vogt E, Marintchev A, Tanaka J, Fagotto F, Altmann M, Wagner G, Pelletier J. Lindqvist L, et al. Among authors: cencic r. PLoS One. 2008 Feb 13;3(2):e1583. doi: 10.1371/journal.pone.0001583. PLoS One. 2008. PMID: 18270573 Free PMC article.

2

RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.

Bordeleau ME, Cencic R, Lindqvist L, Oberer M, Northcote P, Wagner G, Pelletier J. Bordeleau ME, et al. Among authors: cencic r. Chem Biol. 2006 Dec;13(12):1287-95. doi: 10.1016/j.chembiol.2006.10.005. Chem Biol. 2006. PMID: 17185224

3

Homogenous time resolved fluorescence assay to identify modulators of cap-dependent translation initiation.

Cencic R, Yan Y, Pelletier J. Cencic R, et al. Comb Chem High Throughput Screen. 2007 Mar;10(3):181-8. doi: 10.2174/138620707780126688. Comb Chem High Throughput Screen. 2007. PMID: 17346117

4

Identifying small molecule inhibitors of eukaryotic translation initiation.

Cencic R, Robert F, Pelletier J. Cencic R, et al. Methods Enzymol. 2007;431:269-302. doi: 10.1016/S0076-6879(07)31013-6. Methods Enzymol. 2007. PMID: 17923239 Review.

5

c-Myc and eIF4F are components of a feedforward loop that links transcription and translation.

Lin CJ, Cencic R, Mills JR, Robert F, Pelletier J. Lin CJ, et al. Among authors: cencic r. Cancer Res. 2008 Jul 1;68(13):5326-34. doi: 10.1158/0008-5472.CAN-07-5876. Cancer Res. 2008. PMID: 18593934

6

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.

Cencic R, Carrier M, Galicia-Vázquez G, Bordeleau ME, Sukarieh R, Bourdeau A, Brem B, Teodoro JG, Greger H, Tremblay ML, Porco JA Jr, Pelletier J. Cencic R, et al. PLoS One. 2009;4(4):e5223. doi: 10.1371/journal.pone.0005223. Epub 2009 Apr 29. PLoS One. 2009. PMID: 19401772 Free PMC article.

7

Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.

Robert F, Williams C, Yan Y, Donohue E, Cencic R, Burley SK, Pelletier J. Robert F, et al. Among authors: cencic r. Chem Biol Drug Des. 2009 Jul;74(1):57-67. doi: 10.1111/j.1747-0285.2009.00827.x. Chem Biol Drug Des. 2009. PMID: 19519745 Free PMC article.

8

Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells.

Cencic R, Carrier M, Trnkus A, Porco JA Jr, Minden M, Pelletier J. Cencic R, et al. Leuk Res. 2010 Apr;34(4):535-41. doi: 10.1016/j.leukres.2009.07.043. Epub 2009 Sep 1. Leuk Res. 2010. PMID: 19726085 Free PMC article.

9

Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation.

Roche SP, Cencic R, Pelletier J, Porco JA Jr. Roche SP, et al. Among authors: cencic r. Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6533-8. doi: 10.1002/anie.201003212. Angew Chem Int Ed Engl. 2010. PMID: 20687060 Free PMC article. No abstract available.

10

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F.

Cencic R, Hall DR, Robert F, Du Y, Min J, Li L, Qui M, Lewis I, Kurtkaya S, Dingledine R, Fu H, Kozakov D, Vajda S, Pelletier J. Cencic R, et al. Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1046-51. doi: 10.1073/pnas.1011477108. Epub 2010 Dec 29. Proc Natl Acad Sci U S A. 2011. PMID: 21191102 Free PMC article.

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