Covey DF - Search Results

1

Neurosteroid analogues. 14. Alternative ring system scaffolds: GABA modulatory and anesthetic actions of cyclopenta[b]phenanthrenes and cyclopenta[b]anthracenes.

Scaglione JB, Jastrzebska I, Krishnan K, Li P, Akk G, Manion BD, Benz A, Taylor A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Scaglione JB, et al. Among authors: covey df. J Med Chem. 2008 Mar 13;51(5):1309-18. doi: 10.1021/jm701128r. Epub 2008 Feb 15. J Med Chem. 2008. PMID: 18275132

2

Effects of a benz[e]indene on gamma-aminobutyric acid-gated chloride currents in cultured postnatal rat hippocampal neurons.

Rodgers-Neame NT, Covey DF, Hu Y, Isenberg KE, Zorumski CF. Rodgers-Neame NT, et al. Among authors: covey df. Mol Pharmacol. 1992 Dec;42(6):952-7. Mol Pharmacol. 1992. PMID: 1282665

3

Synthesis and structure-activity studies of alkyl-substituted gamma-butyrolactones and gamma-thiobutyrolactones: ligands for the picrotoxin receptor.

Canney DJ, Holland KD, Levine JA, McKeon AC, Ferrendelli JA, Covey DF. Canney DJ, et al. Among authors: covey df. J Med Chem. 1991 Apr;34(4):1460-7. doi: 10.1021/jm00108a034. J Med Chem. 1991. PMID: 1849999

4

Trifluoromethylacetylenic alcohols as affinity labels: inactivation of estradiol dehydrogenase by a trifluoromethylacetylenic secostradiol.

Lawate SS, Covey DF. Lawate SS, et al. Among authors: covey df. J Med Chem. 1990 Sep;33(9):2319-21. doi: 10.1021/jm00171a002. J Med Chem. 1990. PMID: 2391679 No abstract available.

5

Alpha-substituted thiobutyrolactones potentiate GABA currents in voltage-clamped chick spinal cord neurons.

Baker K, Yang J, Covey DF, Clifford DB, Zorumski CF. Baker K, et al. Among authors: covey df. Neurosci Lett. 1988 Apr 22;87(1-2):133-8. doi: 10.1016/0304-3940(88)90158-9. Neurosci Lett. 1988. PMID: 2454424

6

Convulsant gamma-butyrolactones block GABA currents in cultured chick spinal cord neurons.

Zorumski CF, Yang J, Baker K, Covey DF, Clifford DB. Zorumski CF, et al. Among authors: covey df. Brain Res. 1989 Apr 10;484(1-2):102-10. doi: 10.1016/0006-8993(89)90352-1. Brain Res. 1989. PMID: 2713674

7

Effects of steroid D-ring modification on suicide inactivation and competitive inhibition of aromatase by analogues of androsta-1,4-diene-3,17-dione.

Sherwin PF, McMullan PC, Covey DF. Sherwin PF, et al. Among authors: covey df. J Med Chem. 1989 Mar;32(3):651-8. doi: 10.1021/jm00123a026. J Med Chem. 1989. PMID: 2918514

8

Neurosteroid analogues. 3. The synthesis and electrophysiological evaluation of benz[e]indene congeners of neuroactive steroids having the 5 beta-configuration.

Han M, Hu Y, Zorumski CF, Covey DF. Han M, et al. Among authors: covey df. J Med Chem. 1995 Oct 27;38(22):4548-56. doi: 10.1021/jm00022a021. J Med Chem. 1995. PMID: 7473583

9

Neurosteroid analogues: structure-activity studies of benz[e]indene modulators of GABAA receptor function. 1. The effect of 6-methyl substitution on the electrophysiological activity of 7-substituted benz[e]indene-3-carbonitriles.

Hu Y, Zorumski CF, Covey DF. Hu Y, et al. Among authors: covey df. J Med Chem. 1993 Nov 26;36(24):3956-67. doi: 10.1021/jm00076a025. J Med Chem. 1993. PMID: 8254624

10

Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.

Peterson EM, Xu K, Holland KD, McKeon AC, Rothman SM, Ferrendelli JA, Covey DF. Peterson EM, et al. Among authors: covey df. J Med Chem. 1994 Jan 21;37(2):275-86. doi: 10.1021/jm00028a011. J Med Chem. 1994. PMID: 8295215

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